Insulin Saliva Collection
Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Fasting insulin levels in saliva correlate well with levels in serum. If fasting insulin levels are of interest, do not consume food or beverage within eight hours prior to saliva collection. If insulin levels following a glucose challenge are of interest, please be advised that [...]IL-8 Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations Studies show that levels of IL-8 in the oral fluid of healthy individuals do not reflect the levels of IL-8 in circulation. Levels of IL-8 in saliva may only represent individual differences in the degree of inflammation in the oral mucosal immune compartment. This analyte is sensitive [...]Estrone Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations Estrogens are components of various medications and use of these substances can influence the levels measured in saliva. The medications may be delivered via gels, oral tablets, and inhalers. Document use of estrogen containing contraceptives. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling [...]Estriol Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations Estrogens are components of various medications and use of these substances can influence the levels measured in saliva. The medications may be delivered via gels, oral tablets, and inhalers. Document use of estrogen containing contraceptives. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling [...]Estradiol Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations Estrogens are components of various medications and use of these substances can influence the levels measured in saliva. The medications may be delivered via gels, oral tablets, and inhalers. Document use of estrogen containing contraceptives and consider recording the menstrual cycle day count or equivalent. This analyte [...]DHEA-S Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations DHEA(S) is available over the counter in some areas as a supplement. Document use within 12 hours prior to sample collection. Unlike DHEA, levels of DHEA-S in saliva do not correlate as highly with serum levels. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and [...]DHEA Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations DHEA(S) is available over the counter in some areas as a supplement. Document use within 12 hours prior to sample collection. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling should be carefully designed to minimize the impact of freeze-thaw cycles. Consider documenting parameters [...]Cotinine Saliva Collection
Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Salimetrics cotinine assay is designed to be highly sensitive so that discrimination can be made between primary and secondary tobacco smoke exposure. However, levels of cotinine in known heavy smokers will be outside of Salimetrics’ assay range and must be assayed after dilution. Cotinine is [...]C-Reactive Protein Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations Levels of CRP are expected to be low and stable across time unless the donor has a systemic infection. In the latter case, levels of CRP in saliva may be extremely high. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling should be carefully [...]Androstenedione Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations Consider documenting parameters to estimate saliva flow-rate (ie; time taken to collect and sample volume). Consistency in collection method is recommended to avoid introducing unsystematic error into your study data. Saliva Collection Protocol Before Sample Collection Avoid foods with high sugar, acidity, or caffeine immediately before sample [...]Alpha-Amylase Saliva Collection
Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Consider documenting parameters to estimate saliva flow-rate (ie; time taken to collect and sample volume). Consistency in collection method is recommended to avoid introducing unsystematic error into your study data. If collecting with swab devices, it is important to know that concentrations of this analyte [...]Aldosterone Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations Licorice (real) mimics aldosterone and should be avoided 2 weeks before collection. Posture affects aldosterone levels. We recommend sampling after 30 minutes in a resting position. Saliva Collection Protocol Before Sample Collection Avoid foods with high sugar, acidity, or caffeine immediately before sample collection. Document consumption of [...]Cortisol Saliva Collection
Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Bovine hormones normally present in dairy products can cross-react with anti-cortisol antibodies and cause false results. Hormone based oral contraceptives and estrogens, may potentially interfere with cortisol levels in saliva Some steroid-based anti-inflammatory medications and multiple medications mimic the structure of cortisol and have the [...]17 Alpha-OHP Saliva Collection
Print Approved Collection Methods Passive Drool Special Considerations This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling should be carefully designed to minimize the impact of freeze-thaw cycles. Consider documenting parameters to estimate saliva flow-rate (ie; time taken to collect and sample volume). Consistency in collection method is recommended to avoid introducing [...]Salivary Uric Acid
Salivary uric acid may be a useful biomarker for oxidative stress research and monitoring metabolic syndrome to help mitigate cardiometabolic risk. Several studies have reported that a linear relationship exists between uric acid levels in serum and saliva. Uric acid is the most prevalent antioxidant in blood and minimizes the systemic physiological stress of free-radical […]