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Salivary IgM

Technical Summary

Analyte Summary
Analyte: Total Immunoglobulin M
Aliases: IgM
Serum-Saliva Correlation: NA
Optimum Collection Volume: 50 μL*
*Add 300 µl to the total volume of all tests for liquid handling
Assay Summary
Methodology: ELISA
Sensitivity: 0.03 ng/mL
Assay Range: 0.39 – 25 ng/mL
Assay Type: Quantitative

Collect Saliva Samples

IgM SALIVA COLLECTION CONSIDERATIONS

Better results begin with better saliva collection. This collection protocol features general considerations to maximize salivary immunoglobulin M analysis. Use this analyte specific collection protocol to plan your collection methodology and sampling schemes.

Test Saliva Samples

@ Salimetrics
Salimetrics SalivaLab - Easy & Accurate
Order Code (lab): 5176
Transport Requirements: Ship on Dry Ice
@ Your Own Lab
Salimetrics Assay Kits - Better Results

Add DNA Analysis to My Study

Considerations for adding Salivary DNA to analyte Studies:

You can combine salivary analytes with easy, accurate, and affordable genomic testing using Salimetrics SalivaLab and the same sample that you are already collecting – no specialized saliva collection devices or additional samples are required.

Don’t know what SNPs are right for you? The SalivaLab’s DNA team specializes in genetic testing services, we recommend you Request a DNA Consult (gratis) to learn more about common considerations such as # of samples, participant ethnicity, and IRB Approval.

All DNA Services

DNA Extraction and Normalization
Single Nucleotide Polymorphism (SNP) Genotyping
VNTR & STR Analysis

References & Salivary IgM Research

  1. Fereidan-Esfahani M, Nayfeh T, Warrington A, Howe CL, Rodriguez M. IgM Natural Autoantibodies in Physiology and the Treatment of Disease. Methods in molecular biology. 2019;1904:53-81.
  2. Michaud E, Mastrandrea C, Rochereau N, Paul S. Human Secretory IgM: An Elusive Player in Mucosal Immunity. Trends Immunol. 2020;41(2):141-56.
  3. Madar R, Straka S, Baska T. Detection of antibodies in saliva–an effective auxiliary method in surveillance of infectious diseases. Bratisl Lek Listy. 2002;103(1):38-41.
  4. Brandtzaeg P. Do salivary antibodies reliably reflect both mucosal and systemic immunity? Annals of the New York Academy of Sciences. 2007;1098:288-311.
Contact: Salimetrics (USA)
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RESTART YOUR SAMPLE COLLECTION

Safe Saliva Collection in the COVID-19 Era
We have Good News!

Successfully recalibrate your saliva collection and handling procedures with these new safety and compliance guidelines for the COVID-19 era. These guidelines are good practice, easy to follow, and will allow you to begin or continue your research during this historical period of stress and unease… (Read More)

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