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Salivary Transferrin

Technical Summary

Analyte Summary
Analyte: Transferrin
Aliases: Blood Contamination
Serum-Saliva Correlation: NA
Optimum Test Volume: 75 μL*
*Add 300 µl to the total volume of all tests for liquid handling
Assay Summary
Methodology: ELISA
Sensitivity: 0.08 mg/dL
Assay Range: 0.08 mg/dL - 6.6 mg/dL
Assay Type: Quantitative

Collect Saliva Samples


High levels of transferrin measured in saliva indicate the presence of blood contamination and serve as a warning to investigators that samples should be excluded from subsequent quantitative assays for salivary analytes and statistical analyses. Saliva samples collected from populations that have little or no dental care, or known oral health problems, are especially appropriate for screening with the Blood Contamination Assay Kit.​ To screen your samples for blood contamination, we recommend an optimum collection volume of 75 μL in addition to the volume required to perform analysis on your analytes of interest.

Test Saliva Samples

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Salimetrics SalivaLab - Easy & Accurate
Order Code (lab): 5300
Transport Requirements: Ship on Dry Ice
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Salimetrics Assay Kits - Better Results

Add DNA Analysis to My Study

Considerations for adding Salivary DNA to analyte Studies:

You can combine salivary analytes with easy, accurate, and affordable genomic testing using Salimetrics SalivaLab and the same sample that you are already collecting – no specialized saliva collection devices or additional samples are required.

Don’t know what SNPs are right for you? The SalivaLab’s DNA team specializes in genetic testing services, we recommend you Request a DNA Consult (gratis) to learn more about common considerations such as # of samples, participant ethnicity, and IRB Approval.

All DNA Services

DNA Extraction and Normalization
Single Nucleotide Polymorphism (SNP) Genotyping
VNTR & STR Analysis

References & Salivary Transferrin Research

  1. Malamud, D., & Tabak, L. (Eds.). (1993).  Saliva as a diagnostic fluid. Ann N Y Acad Sci, (Vol. 694).  New York, NY.
  2. Kivlighan, K.T., Granger, D.A., Schwartz, E.B., et al. (2004). Quantifying blood leakage into the oral mucosa and its effects on the measurement of cortisol, dehydroepiandrosterone, and testosterone in saliva.  Horm Behav, 46(1), 39-46.
  3. Schwartz, E., & Granger, D.A. (2004). Transferrin enzyme immunoassay for quantitative monitoring of blood contamination in saliva. Clin Chem, 50(3), 654-656.
  4. Granger, D.A., Cicchetti, D., Rogosch, F., et al. (2007).  Blood contamination in children’s saliva: Prevalence, stability, and impact on the measurement of salivary cortisol, testosterone, and dehydroepiandrosterone.  Psychoneuroendocrinology, 32(6), 724-33.
Contact: Salimetrics (USA)
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