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Mineralocorticoid Receptor – MR, NR3C2

Biomarkers

TECHNICAL SUMMARY

Gene Summary
Gene: Mineralocorticoid Receptor
Gene Symbol: MR,MLR, or MCR
Also Known As: NR3C2
Related Analyte(s): Cortisol
Assay Methodology
Genomic DNA, purified using silica based membrane columns is analyzed by TaqMan® SNP Genotyping Assays run on the 7900HT real time PCR system
Yield: 2-5 ug genomic DNA
Biomarkers

How to collect Mineralocorticoid Receptor – MR, NR3C2

APPROVED SALIVARY DNA COLLECTION METHODS

References & MR Related Research

  1. Kellendonk, C. et al (2002). Corticosteroid receptors in the brain: gene targeting studies. Brain Research Bulletin. 57(1), 73-83
  2. Rogerson, FM. et al (2003). Dissecting mineralocorticoid receptor structure and function. Journal of Steroid Biochemistry & Molecular Biology. 85(2-5), 389-396.
  3. Funder, JW. Et al (2005). Mineralocorticoid receptors: distribution and activation. Heart Failure Reviews. 10(1), 15-22
  4. DeRijk, R. et al (2005). Corticosteroid receptor genetic polymorphisms and stress responsivity. Endocrine. 28(3), 263-270.
  5. Vinkers, CH. Et al (2015). Mineralocorticoid receptor haplotypes sex-dependently moderate depression susceptibility following childhood maltreatment. Psychoneuroendocrinology. 54, 90-102.

How Can we help?

Contact: Salimetrics (USA)
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