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Mineralocorticoid Receptor – MR, NR3C2

Gene Summary
Gene: Mineralocorticoid Receptor
Gene Symbol: MR,MLR, or MCR
Also Known As: NR3C2
Related Analyte(s): Cortisol
Assay Methodology
Genomic DNA, purified using silica based membrane columns is analyzed by TaqMan® SNP Genotyping Assays run on the 7900HT real time PCR system
Yield: 2-5 ug genomic DNA

Collect Saliva Samples


Better results begin with better saliva collection. This collection protocol features general considerations to maximize salivary DNA analysis. Use this collection protocol to plan your collection methodology and sampling schemes.


Test Saliva Samples

@ Salimetrics
Salimetrics SalivaLab - Easy & Accurate
Order Code (lab): 5811 (SNP Genotyping)
Transport Requirements: Ship on Dry Ice
@ Your Own Lab
Salimetrics Assay Kits - Better Results

The validated method used by Salimetrics is proprietary and not available in assay kit form at this time.

References & MR Related Research

  1. Kellendonk, C. et al (2002). Corticosteroid receptors in the brain: gene targeting studies. Brain Research Bulletin. 57(1), 73-83
  2. Rogerson, FM. et al (2003). Dissecting mineralocorticoid receptor structure and function. Journal of Steroid Biochemistry & Molecular Biology. 85(2-5), 389-396.
  3. Funder, JW. Et al (2005). Mineralocorticoid receptors: distribution and activation. Heart Failure Reviews. 10(1), 15-22
  4. DeRijk, R. et al (2005). Corticosteroid receptor genetic polymorphisms and stress responsivity. Endocrine. 28(3), 263-270.
  5. Vinkers, CH. Et al (2015). Mineralocorticoid receptor haplotypes sex-dependently moderate depression susceptibility following childhood maltreatment. Psychoneuroendocrinology. 54, 90-102.
Contact: Salimetrics (USA)
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Salimetrics’ COVID-19 Status – 6 April 2020 – No change to Prior Update:

Salimetrics’ Sales and Customer Service, as well as all other non-laboratory personnel, have successfully transitioned to working remote and are fully able to provide support to our customers.

Our Salimetrics Pennsylvania Manufacturing Center remains open for customer orders and shipments. All Salimetrics’ laboratory personnel are following PPE guidelines per CDC Biosafety Level 2 (BSL-2).

The Salimetrics’ SalivaLab, located in California, is open to receive samples. In accordance with State of California Executive Order N-33-20 effective March 19, 2020, our Carlsbad, California facility, including R&D and SalivaLab personnel, will remain open working on research critical to the COVID-19 response; onsite SalivaLab personnel will be able to receive samples, and in some cases, test and send data.  All Salimetrics’ laboratory personnel are following PPE guidelines per CDC Biosafety Level 2 (BSL-2).



COVID-19 Notice