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Salivary Insulin

Technical Summary

Analyte Summary
Analyte: Insulin
Aliases: INS, IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10
Serum-Saliva Correlation: 0.92
Optimum Collection Volume: 100 μL
Special Considerations
Fasting Insulin: Do not consume food or beverage within eight hours prior to saliva collection.

Glucose Challenge: Salivary insulin levels lag approximately 1 hour behind blood levels.
Assay Summary
Methodology: ELISA
Sensitivity: 15 pg/mL
Assay Range: -------
Assay Type: Quantitative

Collect Saliva Samples

INSULIN SALIVA COLLECTION CONSIDERATIONS

Better results begin with better saliva collection. This collection protocol features general considerations to maximize salivary Insulin analysis. Use this analyte specific collection protocol to plan your collection methodology and sampling schemes.

APPROVED SALIVARY INSULIN COLLECTION METHODS

Test Saliva Samples

@ Salimetrics
Salimetrics SalivaLab - Easy & Accurate
Order Code (lab): 5452
Transport Requirements: Ship on Dry Ice
@ Your Own Lab
Salimetrics Assay Kits - Better Results

The validated method used by Salimetrics is proprietary and not available in assay kit form at this time.

Add DNA Analysis to My Study

Considerations for adding Salivary DNA to analyte Studies:

You can combine salivary analytes with easy, accurate, and affordable genomic testing using Salimetrics SalivaLab and the same sample that you are already collecting – no specialized saliva collection devices or additional samples are required.

Don’t know what SNPs are right for you? The SalivaLab’s DNA team specializes in genetic testing services, we recommend you Request a DNA Consult (gratis) to learn more about common considerations such as # of samples, participant ethnicity, and IRB Approval.

All DNA Services

DNA Extraction and Normalization
Single Nucleotide Polymorphism (SNP) Genotyping
VNTR & STR Analysis

References & Salivary Insulin Research

  1. Goodson, JM, et al. (2014). Metabolic Disease Risk in Children by Salivary Biomarker Analysis. PLoS One. 9(6): e98799.
  2. Fekete Z, et al. (1993). Salivary and plasma insulin levels in man. Biochem Mol Biol Int. 30(4): 623–629.
  3. Fabre B, et al. (2012). Measurement of fasting salivary insulin and its relationship with serum insulin in children. Endocr Connect. 1(2): 58–61.
  4. Hartman ML, et al. (2016). Unhealthy Phenotype as Indicated by Salivary Biomarkers: Glucose, Insulin, VEGF-A, and IL-12p70 in Obese Kuwaiti Adolescents. J Obes. 2016: 6860240.
  5. Ebbeling CB, et al. (2002). Childhood obesity: public-health crisis, common sense cure. Lancet. 360(9331):473-82.
  6. Zhao X, et al. (2016). Using Metabolomic Profiles as Biomarkers for Insulin Resistance in Childhood Obesity: A Systematic Review. J Diabetes Res. 2016:8160545.
  7. D’Adamo E, et al. (2011). Type 2 diabetes in youth: epidemiology and pathophysiology. Diabetes Care. 34 Suppl 2:S161-5.
  8. Hayashi T, et al. (2013). Patterns of Insulin Concentration During the OGTT Predict the Risk of Type 2 Diabetes in Japanese Americans. Diabetes. 36(5): 1229-1235.