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Dopamine Receptor – DRD2

Biomarkers

TECHNICAL SUMMARY

Gene Summary
Gene: Dopamine Receptor
Gene Symbol: DRD2
Related Analyte(s): Cotinine, Cortisol
Assay Methodology
Genomic DNA, purified using silica based membrane columns is analyzed by TaqMan® SNP Genotyping Assays run on the 7900HT real time PCR system
Yield: 2-5 ug genomic DNA
Biomarkers

How to collect Dopamine Receptor – DRD2

APPROVED SALIVARY DNA COLLECTION METHODS

References & DRD2 Related Research

  1. Jaber, M. et al. (1996). Dopamine Receptors and Brain Function. Neuropharmacology. 35(11), 1503-1519.
  2. Donald C. Cooper, (2008). Introduction to Neuroscience I, pp. 90
  3. Doehring, A et al (2009). Genetic diagnostics of functional variants of the human dopamine D2 receptor gene. Psychiatric Genetics. 19(5), 259-268.
  4. Glatt, SJ et al (2006). The Cys allele of the DRD2 Ser311Cys polymorphism has a dominant effect on risk for schizophrenia: evidence from fixed- and random-effects meta-analyses. American Journal of Medical Genetics: Neuropsychiatric Genetics. 41B(2), 149-154.
  5. Clarke, TK. et al. (2014). The Dopamine Receptor D2 (DRD2) SNP rs1076560 is Associated with Opioid Addiction. Annals of human genetics. 78(1), 33-39.

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