It appears that your browser may be outdated and performance may be limited. The My Study builder is best viewed with the latest internet browsers. However, if you’d prefer to use our standard form, you can access it below.

Go to Internet Explorer Quick Quote Form

Dismiss this message

C-Reactive Protein Saliva Collection

Approved Collection Methods

Passive Drool

Special Considerations

Levels of CRP are expected to be low and stable across time unless the donor has a systemic infection.  In the latter case, levels of CRP in saliva may be extremely high.

This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling should be carefully designed to minimize the impact of freeze-thaw cycles.

Consider documenting parameters to estimate saliva flow-rate (ie; time taken to collect and sample volume). Consistency in collection method is recommended to avoid introducing unsystematic error into your study data.

Saliva Collection Protocol

Before Sample Collection

  • Avoid foods with high sugar, acidity, or caffeine immediately before sample collection.
  • Document consumption of alcohol, caffeine, nicotine, and prescription/over-the-counter medications within the prior 12 hours.
  • Document vigorous physical activity and the presence of oral disease, injury or inflammation.
  • Do not brush teeth or eat a major meal within 60 minutes of sample collection.
  • Rinse mouth with water to remove food residue and then wait at least 10 minutes before collecting saliva.

During Sample Collection

  • Recommended Collection Volume: 225 µl*
  • Use a collection device that has been validated for the measurement of this analyte.
  • Follow your selected sample collection device/method protocol.

*Add 300 µl to the total volume of all tests for liquid handling

After Sample Collection

  • Record the time and date of specimen collection.
  • Refrigerate samples immediately (if possible) and freeze at or below -20°C (household freezer) as soon as possible (within 6 hours of sample collection)
  • Samples visibly contaminated with blood should be recollected.
  • Do not add preservatives to saliva samples unless it has been previously validated with the assay.
  • Consider aliqouting samples to avoid multiple freeze-thaws.
WordPress Cookie Plugin by Real Cookie Banner
Contact: Salimetrics (USA)
View All International Distributors

New from Salimetrics!

Ready-to-go Customized Participant Collection Packs For Your Study

The best value for your study.

Learn More

OR CALL 800.790.2258

X
Saliva Collection Packs