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Salivary ​Interleukin-5

Technical Summary

Analyte Summary
Analyte: Interleukin-5
Aliases: IL-5, EDF
Serum-Saliva Correlation: NA
Optimum Collection Volume: 100 μL
Assay Summary
Methodology: ECL
Sensitivity: 0.22 pg/mL
Assay Range: 0.22 – 562 pg/mL
Assay Type: Quantitative

Collecting Saliva for Cytokines

CYTOKINE SALIVA COLLECTION CONSIDERATIONS

Better results begin with better saliva collection. This collection protocol features general considerations to maximize salivary cytokine analysis. Use this analyte specific collection protocol to plan your collection methodology and sampling schemes.

APPROVED SALIVARY CYTOKINE COLLECTION METHODS

Test Saliva Samples

@ Salimetrics
Salimetrics SalivaLab - Easy & Accurate
Order Code (lab): 5209.07
Transport Requirements: Ship on Dry Ice
Related Panels and Profiles: Salivary Cytokine Panel
@ Your Own Lab
Salimetrics Assay Kits - Better Results

The validated method used by Salimetrics is proprietary and not available in assay kit form at this time.

Add DNA Analysis to My Study

Considerations for adding Salivary DNA to analyte Studies:

You can combine salivary analytes with easy, accurate, and affordable genomic testing using Salimetrics SalivaLab and the same sample that you are already collecting – no specialized saliva collection devices or additional samples are required.

Don’t know what SNPs are right for you? The SalivaLab’s DNA team specializes in genetic testing services, we recommend you Request a DNA Consult (gratis) to learn more about common considerations such as # of samples, participant ethnicity, and IRB Approval.

All DNA Services

DNA Extraction and Normalization
Single Nucleotide Polymorphism (SNP) Genotyping
VNTR & STR Analysis

References & Salivary IL-5 Research

  1. Dubucquoi S, Desreumaux P, Janin A, Klein O, Goldman M, Tavernier J, et al. (1994). Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J Exp Med. 179(2):703-8.
  2. Yanagibashi T, Satoh M, Nagai Y, Koike M, Takatsu K. (2017). Allergic diseases: From bench to clinic – Contribution of the discovery of interleukin-5. Cytokine. 98:59-70.
  3. Narendra DK, Hanania NA. (2019). Targeting IL-5 in COPD. Int J Chron Obstruct Pulmon Dis. 14:1045-51.
  4. Busse W, Chupp G, Nagase H, Albers FC, Doyle S, Shen Q, et al. (2019). Anti-IL-5 treatments in patients with severe asthma by blood eosinophil thresholds: Indirect treatment comparison. J Allergy Clin Immunol. 143(1):190-200 e20.
  5. Ballou SP, Lozanski G. (1992). Induction of inflammatory cytokine release from cultured human monocytes by C-reactive protein. Cytokine. 4(5):361-8.
Contact: Salimetrics (USA)
View All International Distributors

RESTART YOUR SAMPLE COLLECTION

Safe Saliva Collection in the COVID-19 Era
We have Good News!

Successfully recalibrate your saliva collection and handling procedures with these new safety and compliance guidelines for the COVID-19 era. These guidelines are good practice, easy to follow, and will allow you to begin or continue your research during this historical period of stress and unease… (Read More)

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