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Salivary Bioscience News

*Note: Salimetrics provides this information for research use only (RUO). Information is not provided to promote off-label use of medical devices. Please consult the full-text article.

Measuring Salivary Cortisol to Examine Latent Trait Cortisol and Early Life Stress

Early life stress and latent trait cortisol in adolescent girls: a prospective examination Vergara-Lopez, et al., (2021) Stress ABSTRACT: (1) Early life stress (ELS) may become embedded into an individual’s stress physiology, changing their hypothalamic-pituitary-adrenal (HPA)-axis in an enduring, trait-like fashion. Cortisol is often utilized to investigate HPA-axis function. However, for “trait” cortisol to be […]

Saliva recommended for diagnosing COVID-19 due to higher viral load in comparison with nasopharyngeal swabs

Saliva is superior over nasopharyngeal swab for detecting SARS-CoV2 in COVID-19 patients Beyene GT, et al., (2021) Scientific Reports ABSTRACT: (1) Scaling up of diagnostic capacity is needed to mitigate the global pandemic of SARS-CoV2. However, there are challenges including shortage of sample collection swabs and transport medium. Saliva has been recommended as a simple, […]

A modified bit device can be used to measure saliva in horses

Evaluation of a Modified Bit Device to Obtain Saliva Samples from Horses Vincent, A, et al., (2021) veterinary sciences ABSTRACT: (1) Background: Accounting for the well-being of equine partners is a responsibility of those engaged in Equine-Assisted Services (EAS). Researchers took heed of this call to action by developing an innovative way to collect data […]

Saliva as a potential sample type for lithium monitoring to help improve treatment for patients with mood disorders

Saliva testing as a means to monitor therapeutic lithium levels in patients with psychiatric disorders: Identification of clinical and environmental covariates, and their incorporation into a prediction model Parkin M G, et al., (2021) Bipolar Disorders ABSTRACT: Objective: The narrow therapeutic window of lithium medications necessitates frequent serum monitoring, which can be expensive and inconvenient […]

Salivary Bioscience News

Investigating acute stress and working memory in youth with salivary cortisol and alpha-amylase

Stress and working memory in children and adolescents: Insights from a multisystem approach Tsai, et al., (2021) Journal of Experimental Child Psychology ABSTRACT: Despite considerable research with adults suggesting that acute stress negatively affects working memory (WM), a core cognitive function, few studies have assessed these effects in youths. Studies that have been conducted have […]

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Salimetrics Expands Laboratory CLIA Certification for Saliva Testing

(February 2, 2022) Saliva testing is gaining in its utility to provide screening and diagnostic solutions, and Salimetrics is here to meet the needs of this growing field. With the recent expansion of Salimetrics' CLIA certification, the Saliva Laboratory reaches a new milestone in salivary bioscience. Salimetrics Saliva Laboratory’s experienced team, combined with the expanded [...]
COVID-19 in Saliva

Salimetrics’ Team Supports NIH Funded SARS-CoV-2 Post-Vaccination Study of Women’s Health

A new study seeks to investigate SARS CoV-2 vaccine effects on menstruation in female adolescents using salivary bioscience with the support of Salimetrics. While the current SARS-CoV-2 vaccines are considered safe and effective at preventing infection and hospitalizations, some women have reported menstrual cycle changes post-vaccination. Although incidents are low, changes in cycle length and […]

Salivary Bioscience News

Salivary Cortisol and alpha-amylase assayed in ethnic minorities depicts atypical diurnal rhythm

Stress response asymmetries in African American emerging adults exposed to chronic social adversity Wood, et al., (2021) The International Journal on the Biology of Stress ABSTRACT: Chronic stress is linked to social adversity and underlies many health disparities among ethnic minorities. Cortisol and salivary alpha-amylase (sAA) reflect sensitivity to adversity and are related to health […]

Salivary Bioscience News

Trier Social Stress Test: Validating a Remote, TSST-Online Protocol

Validation of an online version of the Trier Social Stress Test in a study of adolescents Gunnar, et al., (2021) Psychoneuroendocrinology ABSTRACT: Introduction: The Trier Social Stress Test (TSST) is the most widely used protocol for activating a stress response of the hypothalamic-pituitary-adrenocortical (HPA) axis and other stress-mediating systems. A number of variants of the […]

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Statistical Approaches to Reduce Bias in Left-censored Salivary Data

Censored Data Considerations and Analytical Approaches for Salivary Bioscience Data Ahmadi, H. et al., (2021) Psychoneuroendorcinology ABSTRACT: Left censoring in salivary bioscience data occurs when salivary analyte determinations fall below the lower limit of an assay’s measurement range. Conventional statistical approaches for addressing censored values (i.e., recoding as missing, substituting or extrapolating values) may introduce […]

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Salivary Bioscience Research for Nordic Region Investigators

Have you met XboXLab? XboXLab is one of Salimetrics trusted international distributors covering the Nordic region (Norway, Finland, Sweden, Denmark). Their team consists of knowledgeable and experienced employees ready to assist researchers and suppliers. XboXLab and Salimetrics both align in their fundamental goal of fulfilling salivary bioscience research needs by providing customers with high-quality SalivaBio […]

Salivary Bioscience News

Blunted Morning Salivary Cortisol Associated with Cardiovascular Risk

Blunted circadian cortisol in children is associated with poor cardiovascular health and may reflect circadian misalignment Dai, W. et al., ( 2021) Psychoneuroendocrinology ABSTRACT: Objectives: Circadian cues in children (sunlight, exercise, diet patterns) may be associated with health outcomes. The primary objective was to assess associations of daily cortisol fluctuations (morning, night) with cardiovascular health […]

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Salivary cortisol correlates with DNA methylation in preterm infants

DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function Padbury, J. et al., (2021) Pediatric Research ABSTRACT: Background: There is increased risk of cardiovascular, metabolic, and hypertensive disorders in later life in the preterm population. We studied school-age children who had been born extremely premature who had undergone endocrine, […]

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Salivary SARS-CoV-2 IgG Assay: A practical alternative for screening and monitoring vaccine antibody response and seroprevalence.

Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers Heaney et al., ( 2021) medRxiv ABSTRACT: Oral fluid (hereafter saliva) offers a non-invasive sampling method for the detection of SARS-CoV-2 antibodies. However, data comparing performance of salivary tests against commercially-available serologic and neutralizing antibody (nAb) assays are […]

Salivary Bioscience News

The role of Salivary Cortisol and Progesterone in female friendships

The endocrinology of female friendships: Cortisol and progesterone attunement after separation Rankin et al., (2021) Biological Psychology ABSTRACT: Friendships constitute important relationships, and often function to reduce stress, but have been under-studied. In mother-child dyads, infants coordinate their stress response with their caregivers without experiencing the stressor themselves. The current study used a modified version […]

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