It appears that your browser may be outdated and performance may be limited. The My Study builder is best viewed with the latest internet browsers. However, if you’d prefer to use our standard form, you can access it below.

Go to Internet Explorer Quick Quote Form

Dismiss this message

Mu-Opioid Receptor – OPRM1

Biomarkers

TECHNICAL SUMMARY

Gene Summary
Gene: Opioid Receptor, mu 1
Gene Symbol: OPRM1
Related Analyte(s): Cortisol
Common SNPs
rs1799971
Assay Methodology
Genomic DNA, purified using silica based membrane columns is analyzed by TaqMan® SNP Genotyping Assays run on the 7900HT real time PCR system
Yield: 2-5 ug genomic DNA
Biomarkers

How to collect Mu-Opioid Receptor – OPRM1

APPROVED SALIVARY DNA COLLECTION METHODS

References & OPRM1 Related Research

  1. Haerian BS, Haerian MS. (2013). OPRM1 rs1799971 polymorphism and opioid dependence: evidence from a meta-analysis. Pharmacogenomics. PMID: 23651028
  2. Bond C, et al (1998). Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A. PMID: 9689128
  3. van den Wildenberg E, et al. (2007). A functional polymorphism of the mu-opioid receptor gene (OPRM1) influences cue-induced craving for alcohol in male heavy drinkers. Alcohol Clin Exp Res. PMID: 17207095
  4. Ren ZY, et al. (2015). The impact of genetic variation on sensitivity to opioid analgesics in patients with postoperative pain: a systematic review and meta-analysis. Pain Physician. PMID: 25794200
  5. Bart G, et al. (2005). Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology. PMID: 15525999
  6. Way BM, et al. (2009). Variation in the mu-opioid receptor gene (OPRM1) is associated with dispositional and neural sensitivity to social rejection. Proc Natl Acad Sci U S A. PMID: 19706472
  7. Slavich GM, et al. (2014). Endogenous opioid system influences depressive reactions to socially painful targeted rejection life events. Psychoneuroendocrinology. PMID: 25086307
  8. Carver CS, et al. (2015). Mu opioid receptor polymorphism, early social adversity, and social traits. Soc Neurosci. PMID: 26527429
  9. Bergen AW, et al. (1997). Mu opioid receptor gene variants: lack of association with alcohol dependence. Mol Psychiatry. PMID: 9399694

How Can we help?

Contact: Salimetrics (USA)
View All International Distributors

NEW – Salivary Bioscience Webinars

Learn the better methods for getting the most out of your Salivary Bioscience research study.

Check Available Dates

CALL 800.790.2258
ASK AN EXPERT   REQUEST A QUOTE

X
Training Workshops