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Salivary Osteocalcin and its association to psychiatric disorders
Osteocalcin is a bone-derived hormone implicated in the acute stress response and recently linked to adult depression. Yet it is unclear whether osteocalcin is a biomarker of other forms of…
Salivary and serum inflammatory markers relate to worse self rated health
Understanding the biological processes underlying poor self-rated health (SRH) can inform prevention efforts. The COVID-19 pandemic highlighted the importance of using self-reported measures and self-collected biospecimens, such as saliva, to understand…
Understanding Salivary C-Reactive Protein as a Biomarker in Military Personnel
C-reactive protein is a systemic inflammatory biomarker that is positively associated with the development of disease. Salivary C-reactive protein (sCRP) has previously been reported to have a diurnal rhythm with higher levels upon…
Exploring Salivary Metabolomes in Child-Caregiver Dyads: Insights from the Family Life Project
Human metabolism is complex, and is impacted by genetics, cohabitation, diet, health, and environmental inputs. As such, we applied untargeted LC-MS metabolomics to 1425 saliva samples from a diverse group of…
Assessing Maternal Control Strategies Through Infant-Mother Salivary Cortisol Levels
Maternal control strategy refers to a mother’s practices used to impel, inhibit, guide, or shape their children’s behaviors during mother-child interaction. The present study examined control strategies used by Chinese urban mothers and how they associated with…
Evaluating Salivary Uric Acid and Stress Hormones Using the Trier Social Stress Test
Acute physiological responses to psychosocial stressors are a potential pathway underlying racial disparities in stress-related illnesses. Uric acid (UA) is a potent antioxidant that has been linked to disparities in stress-related illnesses, and recent research has shown that UA is…
Fathers’ Alexithymia and Salivary Testosterone Influence Toddlers’ Prosocial Behavior
The development of prosocial skills in children is a key predictor of long-term social, cognitive, and emotional functioning. However, the role of fathers’ psychological characteristics in …
Assessment of the Relationship Between Behavioral and Physiological Parameters and the Emotional Valence and Arousal in Dogs
A complete assessment of animal welfare requires not just an understanding of negative emotional states, such as fear and anxiety, but also of positive states, such as…
Inflammageing and the Interplay of Cytokines, Chemokines, and Growth Factors for Targeted Interventions
Most older individuals develop inflammageing, a condition characterized by elevated levels of blood inflammatory markers that carries high susceptibility to chronic morbidity…
A cluster-randomized trial of water, sanitation, handwashing and nutritional interventions on stress and epigenetic programming
A regulated stress response is essential for healthy child growth and development trajectories. We conducted a cluster-randomized trial in rural Bangladesh (funded by the Bill & Melinda Gates Foundation, ClinicalTrials.gov NCT01590095) to assess the effects of an…
Career Opportunity: Join Naval Health Research Center in San Diego as a Sleep Research Scientist
The Naval Health Research Center (NHRC) is seeking an outstanding Sleep Research Scientist to join our…
Cytokine levels measured in gingival crevicular fluid as an oral health application
With effective antiretroviral therapy, people with HIV (PWH) are living longer and aging; the majority of PWH in the United States are now over the age of 50 and in women have gone through the…
Stress Biomarkers and Child Development in Young Children in Bangladesh
Hundreds of millions of children in low- and middle-income countries are exposed to chronic stressors, such as poverty, poor sanitation and hygiene, and sub-optimal nutrition. These stressors can have…
Salivary metabolomics in the family environment: A large-scale study investigating oral metabolomes in children and their parental caregivers
Human metabolism is complex and dynamic, and is impacted by genetics, diet, health, and countless inputs from the environment. Beyond the genetics shared by family members, cohabitation leads to shared microbial and environmental exposures. Furthermore, metabolism is affected by factors such as…
Association of salivary metals with ADHD
Exposure to toxic heavy metals has been associated with the development of attention-deficit/hyperactivity disorder (ADHD). However, fewer studies have examined the associations between abnormal levels of……