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Censored Data Considerations and Analytical Approaches for Salivary Bioscience Data Ahmadi, H. et al., (2021) Psychoneuroendorcinology ABSTRACT: Left censoring in salivary bioscience data occurs when salivary analyte determinations fall below the lower limit of an assay’s measurement range. Conventional statistical approaches for addressing censored values (i.e., recoding as missing, substituting or extrapolating values) may introduce […]
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Blunted circadian cortisol in children is associated with poor cardiovascular health and may reflect circadian misalignment Dai, W. et al., ( 2021) Psychoneuroendocrinology ABSTRACT: Objectives: Circadian cues in children (sunlight, exercise, diet patterns) may be associated with health outcomes. The primary objective was to assess associations of daily cortisol fluctuations (morning, night) with cardiovascular health […]
DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function Padbury, J. et al., (2021) Pediatric Research ABSTRACT: Background: There is increased risk of cardiovascular, metabolic, and hypertensive disorders in later life in the preterm population. We studied school-age children who had been born extremely premature who had undergone endocrine, […]
Salivary SARS-CoV-2 IgG Assay: A practical alternative for screening and monitoring vaccine antibody response and seroprevalence.
Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers Heaney et al., ( 2021) medRxiv ABSTRACT: Oral fluid (hereafter saliva) offers a non-invasive sampling method for the detection of SARS-CoV-2 antibodies. However, data comparing performance of salivary tests against commercially-available serologic and neutralizing antibody (nAb) assays are […]
The endocrinology of female friendships: Cortisol and progesterone attunement after separation Rankin et al., (2021) Biological Psychology ABSTRACT: Friendships constitute important relationships, and often function to reduce stress, but have been under-studied. In mother-child dyads, infants coordinate their stress response with their caregivers without experiencing the stressor themselves. The current study used a modified version […]
Children’s Altruism Following Acute Stress: The Role of Autonomic Nervous System Activity and Social Support V Alen et al., (2021) Developmental Science ABSTRACT: Altruistic behavior after stress exposure may have important health and psychological benefits, in addition to broader societal consequences. However, so far experimental research on altruism following acute stress has been limited to […]
Neuroscience Meets Salivary Bioscience: Interaction between sex, stress reactivity, and cingulum GFA
Sex-related differences in stress reactivity and cingulum white matter Wheelock, et al., ( 2021) Neuroscience ABSTRACT: The prefrontal cortex and limbic system are important components of the neural circuit that underlies stress and anxiety. These brain regions are connected by white matter tracts that support neural communication including the cingulum, uncinate fasciculus, and the fornix/stria-terminalis. […]
Increased dehydroepiandrosterone (DHEA) is associated with anxiety in adolescent girls Mulligan EM, et al., (2020) Psychneuroendocrinology ABSTRACT: The pubertal period is a time of rapid increase in the incidence of anxiety disorders, and thus, pubertal hormones may play a role in the precipitation of anxious psychopathology. DHEA, a steroid hormone that surges in adolescence, has […]
Child depressive symptoms: Associations with salivary cortisol and alpha amylase in two distinct challenges Khoury JE, et al., ( 2020) Biological psychology ABSTRACT: Child depression has been inconsistency linked to cortisol and salivary alpha-amylase (sAA) reactivity. This study assessed three factors that contribute to inconsistencies: 1) the differential effectiveness of laboratory challenges to elicit cortisol […]