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Diagnostic Salivary Cotinine ELISA Kit (FDA, CE Mark)
Salimetrics Assay #1-2112 (in vitro diagnostic use)
Salimetrics Salivary Cotinine ELISA provides researchers with a sensitive method to objectively quantify differences in individual cotinine levels (nicotine exposure), using an easy to collect, non-invasive saliva-sample. Validated for clinical use, and highly correlated with serum levels, Salimetrics Cotinine assay’s high-sensitivity distinguishes between active smokers, non-smokers, and recent second-hand smoke exposure. Cotinine, the most common biomarker for nicotine exposure analysis, and is primarily measured in smoking cessation studies, e-cigarette and public health research, and to assess second-hand smoke exposure in children. Companies may also evaluate salivary cotinine levels for tobacco use relative to employment, health, and life-insurance purposes. Cotinine is a preferred biomarker to evaluate tobacco use, because it maintains a half-life of up to 16-hours, as opposed to nicotine’s half-life of just several hours.
Van Vunakis, H., Tashkin, D.P., Rigas, B., et al. (1989). Relative sensitivity and specificity of salivary and serum cotinine in identifying tobacco-smoking status of self-reported non-smokers and smokers of tobacco and/or marijuana. Arch Environ Health, 44(1), 53-58.
Watts, R.R., Longone, J.J., Kinght, G.J., & Lewtas, J. (1990). Cotinine analytical workshop report: Consideration of analytical methods for determining cotinine in human body fluids as a measure of passive exposure to tobacco smoke. Environ Health Perspect, 84, 173-82.
Roche, D., Callai, F., Reungoat, P., & Momas, I. (2001). Adaptation of an enzyme immunoassay to assess urinary cotinine in nonsmokers exposed to tobacco smoke. Clin Chem, 47(5), 950-52.
Chard, T. (1990). An introduction to radioimmunoassay and related techniques (4th ed.). Amsterdam: Elsevier.
Granger, D.A., Blair, C., Willoughby, M., Kivlighan, K.T., Hibel, L.C., Fortunato, C.K., Wiegand, L.E., & The Family Life Project Investigators (2007). Individual differences in salivary cortisol and alpha-amylase in mothers and infants: Relation to tobacco smoke exposure. Dev Psychobiol, 49(7), 692-701.
Salimetrics’ COVID-19 Status – 8 April 2020 – No change to Prior Update:
Salimetrics’ Sales and Customer Service, as well as all other non-laboratory personnel, have successfully transitioned to working remote and are fully able to provide support to our customers.
Our Salimetrics Pennsylvania Manufacturing Center remains open for customer orders and shipments. All Salimetrics’ laboratory personnel are following PPE guidelines per CDC Biosafety Level 2 (BSL-2).
The Salimetrics’ SalivaLab, located in California, is open to receive samples. In accordance with State of California Executive Order N-33-20 effective March 19, 2020, our Carlsbad, California facility, including R&D and SalivaLab personnel, will remain open working on research critical to the COVID-19 response; onsite SalivaLab personnel will be able to receive samples, and in some cases, test and send data. All Salimetrics’ laboratory personnel are following PPE guidelines per CDC Biosafety Level 2 (BSL-2).