Zoom Webinar: Christopher D. Heaney, PhD., Johns Hopkins University – Using a Multiplex Salivary Antibody Assay to Measure SARS-CoV-2 Infection and Vaccination at Population-Scale
CHRISTOPHER D. HEANEY, PHD
Bloomberg School of Public Health
Johns Hopkins University
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of an ongoing pandemic that has infected millions of people across the globe. Informed implementation of government public health policies depends on accurate data on SARS-CoV-2 immunity at a population scale. Detection of SARS-CoV-2 salivary antibodies could serve as a noninvasive alternative to serological testing for monitoring of SARS-CoV-2 infection and seropositivity at a population scale. This talk will focus on the development and utility of a saliva-based multiplex SARS-CoV-2 antibody immunoassay based on Luminex technology that comprised 12 CoV antigens, mostly derived from SARS-CoV-2 nucleocapsid (N) and spike (S). The use of saliva-based antibody testing may be a valuable noninvasive and scalable alternative to blood-based antibody testing. Implications for population based and behavioral research will be discussed.
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