Salivary DHEA-Cortisol Ratio Associations with Parental Maltreatment and Juvenile Incarcerated Male Psychopathy
Dehydroepiandrosterone (DHEA) and its ratio to cortisol moderate associations between maltreatment and psychopathology in male juvenile offenders Author: Kimonis ER, et al. (2019), Psychoneuroendocrinology. ABSTRACT This study examined whether DHEA and its ratio to cortisol moderated risk for psychopathology among incarcerated youth exposed to childhood maltreatment. Resistance to stress-related psychopathology under adversity was also examined in […]
Research highlights multi-system perspective for motivation, adolescent depressive symptoms, and HPA axis activation
An exploratory analysis of the joint contribution of HPA axis activation and motivation to early adolescent depressive symptoms. Author: Rudolph KD, et al (2018), Developmental Psychobiology BACKGROUND: This study examines the interactive contribution of the hypothalamic-pituitary-adrenal (HPA) axis and approach-avoidance motivation systems to longitudinal changes in depressive symptoms across the adolescent transition. In the summer […]
Salivary DNA analysis shows exercise reduces genetic risk for depression and suicidal ideation
A genetic risk factor for major depression and suicidal ideation is mitigated by physical activity Author: Taylor MK, et al. (2017), Psychiatry Research We evaluated associations of five candidate polymorphisms (Bcl1 [rs41423247], -2C/G [rs2070951], COMT [rs737865], Val66Met [rs6265], and 5HTTLPR [biallelic and triallelic [5HTTLPR/rs25531]) with probable MDD and suicidal ideation (SI), the effects of physical […]
Study demonstrates combined effects of salivary cortisol & DHEA-S in predicting depressive symptoms
Concurrent and prospective associations between HPA axis activity and depression symptoms in newlywed women Author: Ge F, et al (2016), Psychoneuroendocrinology. We investigated the extent to which individual differences in activity of the hypothalamic pituitary adrenal axis (HPA) are associated with depressive symptoms among newlywed couples. Participants were 218 couples (M age 28.4 years; 94% […]