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Salivary Interleukin-8
Interleukin-8 (IL-8), also known as neutrophil chemotactic factor, belongs to the CXC chemokine family and mainly serves as an immune mediator of neutrophil-dependent acute inflammation (2). IL-8 is produced in…
Salivary Interleukin-1 Beta
…by a number of different cell types, including macrophages, monocytes, fibroblasts, and dendritic cells. (1,2,3) IL-1β is an example of a pro-inflammatory cytokine, since it is involved in the body’s…
Salivary Interleukin-6
Interleukin-6 (IL-6) is one of a family of biologically active small protein molecules known as cytokines. It is released by a variety of tissues, including activated leukocytes, adipocytes, and endothelial…
Salivary Progesterone
…males, progesterone is thought to play some role in testicular physiology. (7) In addition to its role as a sex hormone, progesterone also serves as a precursor compound for many…
Salivary SIgA
Secretory Immunoglobulin A (SIgA) is a subclass of Immunoglobulin A (IgA), an antibody that plays a critical role in mucosal immunity. SIgA is the main immunoglobulin found in mucous secretions…
Salivary TNF-Alpha
*Also available as part of the Salimetrics Cytokine Panel* Tumor necrosis factor alpha (TNF-Alpha) is a member of a family of small biologically active proteins known as cytokines. TNF-α…
Salivary IgG
…all four antibody subclasses. In saliva, IgG diffuses from serum most commonly through gingival crevices but can also be produced locally. IgG levels in saliva are generally in the microgram…
Salivary Alpha-Amylase
…as a marker of activity in the autonomic nervous system. (9,10,11) Salivary alpha-amylase levels have been used as a biomarker of ANS activity in various fields of biobehavioral research. (12,13,14,15)…
Salivary C-Reactive Protein
…including phosphocholine, a common constituent of polysaccharide coatings of bacterial pathogens and mammalian cell membranes. This allows CRP to function as an opsonin, facilitating phagocytosis of pathogens and dead or…
Salivary Cotinine
When nicotine from tobacco smoke is taken into the lungs and enters the bloodstream, the principle metabolite produced in the liver is cotinine. Cotinine diffuses easily from blood into saliva,…
Neuroscience Meets Salivary Bioscience: Interaction between sex, stress reactivity, and cingulum GFA
Sex-related differences in stress reactivity and cingulum white matter Wheelock, et al., ( 2021) Neuroscience ABSTRACT: The prefrontal cortex and limbic system are important components of the neural circuit that…
Increased altruism in children during distress may benefit from “tend-and-befriend” behavior
…important health and psychological benefits, in addition to broader societal consequences. However, so far experimental research on altruism following acute stress has been limited to adult populations. The current study…
The role of Salivary Cortisol and Progesterone in female friendships
…Test to examine whether i) friends are physiologically attuned (i.e., cortisol and progesterone); ii) attunement differs as a function of social acceptance or rejection external to the dyad; and, iii)…
Improved salivary HCMV IgG antibody assays may be a viable option for serum testing
…variables. Compared to the serum test, the salivary HCMV IgG test had 51% sensitivity and 97% specificity. With improvements in assay performance and sample optimization, HCMV antibody levels in oral…
Autonomic and Inflammatory Responses Moderated by Stress Appraisals and Affect
…to characterize healthy responses. Healthy African-Americans (n=115) completed the Trier Social Stress Test, and biological responses were assessed through salivary cortisol, dehydroepiandrosterone-sulfate (DHEA-S), alpha amylase (sAA), and C-reactive protein (sCRP)….