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Salimetrics Assay #1-2212 (in vitro diagnostic use)
The Salimetrics Salivary DHEA Enzyme Immunoassay Kit was specifically designed to standardize the detection of DHEA in saliva samples for research and biomedical laboratories. Using a small sample volume, this assay kit has an extended range that spans the expected DHEA levels found in human saliva. The average inter- and intra-assay precision coefficients of variation are low with no deleterious matrix effects often found in saliva which are characterized through dilution- and spike-recovery validation procedures. This DHEA assay kit has also been formatted to minimize cross reactivity for related steroids.
DHEA is a major secretory product of the adrenal glands; it is co-released along with cortisol in response to ACTH from the pituitary gland. A major role of DHEA is to act as a circulating precursor of androgens and estrogens in tissues throughout the body, and it has also been associated with immune function. In addition, DHEA is produced directly by the nervous system, where it functions as a neuroactive and neuroprotective factor. Salivary DHEA levels are unaffected by salivary flow rate or salivary enzymes. DHEA exhibits a diurnal rhythm similar to cortisol, with highest levels in the morning after awakening, followed by a decline throughout the afternoon and evening.
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Salimetrics’ COVID-19 Status – 6 April 2020 – No change to Prior Update:
Salimetrics’ Sales and Customer Service, as well as all other non-laboratory personnel, have successfully transitioned to working remote and are fully able to provide support to our customers.
Our Salimetrics Pennsylvania Manufacturing Center remains open for customer orders and shipments. All Salimetrics’ laboratory personnel are following PPE guidelines per CDC Biosafety Level 2 (BSL-2).
The Salimetrics’ SalivaLab, located in California, is open to receive samples. In accordance with State of California Executive Order N-33-20 effective March 19, 2020, our Carlsbad, California facility, including R&D and SalivaLab personnel, will remain open working on research critical to the COVID-19 response; onsite SalivaLab personnel will be able to receive samples, and in some cases, test and send data. All Salimetrics’ laboratory personnel are following PPE guidelines per CDC Biosafety Level 2 (BSL-2).