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Analytes in Saliva Quick Reference Guide

Saliva Panel and Profiles

Salivary Cytokine Panel

Salivary DLMO Profile

Target Analyte(s): Salivary Melatonin
Optimum Collection Volume: 500 μL/sample
Sample Test Volume: 100 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 1.37 pg/mL
Assay Range: 0.78-50 pg/mL
Serum-Saliva Correlation: 0.81

Salivary Analytes

Salivary 17 Alpha-OHP

Optimum Collection Volume: 125 μL
Sample Test Volume: 50 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 3 pg/mL
Assay Range: 5.1 pg/mL - 500pg/mL
Serum-Saliva Correlation: 0.64

Salivary Aldosterone

Optimum Collection Volume: 175 μL
Sample Test Volume: 100 µl
Collect With: Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Salimetrics Passive Drool Method
Assay Sensitivity: 35 pg/mL
Assay Range: -----
Serum-Saliva Correlation: 0.75-0.96

Salivary Alpha-Amylase

Optimum Collection Volume: 25 μL
Sample Test Volume: 10 µL of saliva then 8 µL of X200 dilution
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 0.4 U/mL
Assay Range: 2-400 U/mL
Serum-Saliva Correlation: NA

Salivary Androstenedione

Optimum Collection Volume: 125 μL
Sample Test Volume: 50 µL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 5 pg/mL
Assay Range: 10 pg/mL - 2430 pg/mL
Serum-Saliva Correlation: NA

Salivary C-Reactive Protein

Optimum Collection Volume: 225 μL
Sample Test Volume: 150 µL of saliva, 100 µL of x2 dilution
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 1.79 pg/mL
Assay Range: 25 pg/mL - 1600 pg/mL
Serum-Saliva Correlation: NA

Salivary Chromogranin A

Optimum Collection Volume: 75 μL*
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 7 ng/mL
Assay Range: NA
Serum-Saliva Correlation: NA

Salivary Cortisol

Optimum Collection Volume: 75 uL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: <0.007 ug/dL
Assay Range: 0.012-3.000 ug/dL
Serum-Saliva Correlation: 0.91

Salivary Cotinine

Optimum Collection Volume: 75 µL
Sample Test Volume: 20 µL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 0.15 ng/mL
Assay Range: 0.8 ng/mL - 200 ng/mL
Serum-Saliva Correlation: NA

Salivary DHEA

Optimum Collection Volume: 125 μL
Sample Test Volume: 50 µL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 5 pg/mL
Assay Range: 10.2 pg/mL - 1000 pg/mL
Serum-Saliva Correlation: 0.86

Salivary DHEA-S

Optimum Collection Volume: 225 μL
Sample Test Volume: 100 µL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 95.14 pg/mL
Assay Range: 188.9 pg/mL- 15,300 pg/mL
Serum-Saliva Correlation: NA

Salivary Estradiol

Optimum Collection Volume: 225 μL*
Sample Test Volume: 100 µL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.1 pg/mL
Assay Range: 1 pg/mL - 32 pg/mL
Serum-Saliva Correlation: 0.80

Salivary Estriol

Optimum Collection Volume: 175 μL
Sample Test Volume: 100 µL of X2 dilution
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 16 pg/mL
1 pg/mL (HS)
Assay Range: 20 pg/mL - 4860 pg/mL
5 pg/mL - 1215 pg/mL (HS)
Serum-Saliva Correlation: 0.87

Salivary Estrone

Optimum Collection Volume: 255 μL
Sample Test Volume: 100 µL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 1.4 pg/mL
Assay Range: 3.1 pg/mL - 300 pg/mL
Serum-Saliva Correlation: NA

Salivary IgG

Optimum Collection Volume: 50 μL
Sample Test Volume: 10 uL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 0.043 ng/mL
Assay Range: 0.3125 - 20 ng/mL
Serum-Saliva Correlation: NA

Salivary Insulin

Optimum Collection Volume: 100 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 0.39 µIU/mL
Assay Range: 0.39 – 300 µIU/mL
Serum-Saliva Correlation: 0.92

Salivary Interferon Gamma

Optimum Collection Volume: 100 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.37 pg/mL
Assay Range: 0.37 – 4760 pg/mL
Serum-Saliva Correlation: NA

Salivary Interleukin-1 Beta

Optimum Collection Volume: 50 μL
Sample Test Volume: 20 μL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: < 0.37 pg/mL
Assay Range: 3.13 pg/mL - 200 pg/mL
Serum-Saliva Correlation: NA

Salivary Interleukin-2

Optimum Collection Volume: 100 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.09 pg/mL
Assay Range: 0.09 – 6040 pg/mL
Serum-Saliva Correlation:

Salivary Interleukin-6

Optimum Collection Volume: 135 μL
Sample Test Volume: 60 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.07 pg/mL
Assay Range: 1.56 – 100 pg/mL
Serum-Saliva Correlation: NA

Salivary Interleukin-8

Optimum Collection Volume: 100 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.07 pg/mL
Assay Range: 0.07 – 2336 pg/mL
Serum-Saliva Correlation: NA

Salivary Interleukin-10

Optimum Collection Volume: 100 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.04 pg/mL
Assay Range: 0.04 – 1420 pg/m
Serum-Saliva Correlation: NA

Salivary Interleukin-12p70

Optimum Collection Volume: 100 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.11 pg/mL
Assay Range: 0.11 – 2180 pg/mL
Serum-Saliva Correlation:

Salivary Interleukin-13

Optimum Collection Volume: 100 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.24 pg/mL
Assay Range: 0.24 – 2072 pg/mL
Serum-Saliva Correlation: NA

Salivary Melatonin

Optimum Collection Volume: 225 μL
Sample Test Volume: 100 µL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 1.35 pg/mL
Assay Range: 0.78-50 pg/mL
Serum-Saliva Correlation: 0.81

Salivary Neopterin

Optimum Collection Volume: 125 μL*
Sample Test Volume: 50 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.51 ng/mL
Assay Range: -----
Serum-Saliva Correlation: NA

Salivary Osteocalcin

Optimum Collection Volume: 150 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 13.72 pg/mL
Assay Range: 9.77 - 10,000 pg/mL
Serum-Saliva Correlation: N/A

Salivary Oxytocin

Optimum Collection Volume: 150 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 4 pg/mL
Assay Range: 6.4-1000 pg/mL
Serum-Saliva Correlation: N/A

Salivary Progesterone

Optimum Collection Volume: 125 μL
Sample Test Volume: 50 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 5 pg/mL
Assay Range: 10 pg/mL - 2430 pg/mL
Serum-Saliva Correlation: NA

Salivary SARS-CoV-2 (N) IgG

Optimum Collection Volume: 200 μL
Sample Test Volume: 50 uL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 92%
Assay Specificity: 98%
Assay Range: Qualitative
Serum-Saliva Correlation: NA

Salivary SIgA

Optimum Collection Volume: 50 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 2.5 μg/mL
Assay Range: 2.50 µg/mL – 600 µg/mL
Serum-Saliva Correlation:

Salivary Testosterone

Optimum Collection Volume: 75 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 1 pg/mL
Assay Range: 6.1 pg/mL - 600 pg/mL
Serum-Saliva Correlation: 0.96

Salivary TNF-Alpha

Optimum Collection Volume: 425 μL
Sample Test Volume: 200 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.106 pg/mL
Assay Range: 0.04 - 1360 pg/mL
Serum-Saliva Correlation: NA

Salivary Total Protein

Optimum Collection Volume: 75 μL
Sample Test Volume: 25 μL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 5 μg/mL
Assay Range: -----
Serum-Saliva Correlation: NA

Salivary Transferrin

Optimum Collection Volume: 75 μL
Sample Test Volume: 20 µL
Collect With: Salimetrics Passive Drool Method
Assay Sensitivity: 0.08 mg/dL
Assay Range: 0.08 mg/dL - 6.6 mg/dL
Serum-Saliva Correlation: NA

Salivary Uric Acid

Optimum Collection Volume: 25 μL
Sample Test Volume: 10 µL
Collect With: Salimetrics Passive Drool Method
Salimetrics Oral Swab (SOS) Method
Salimetrics Children's Swab (SCS) Method
Salimetrics Infant's Swab (SIS) Method
Assay Sensitivity: 0.07 mg/dL
Assay Range: 0.07- 20 mg/dL
Serum-Saliva Correlation: 0.84
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