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SARS-CoV-2 (N) IgG Saliva Collection

Approved Collection Methods

Passive Drool

SalivaBio Swabs

Special Considerations

Consistency in collection methods and sample handling is recommended for optimal results. Production of volumes larger than 1 mL may produce a diluted sample that may necessitate a recollection.

Saliva Collection Protocol

Before Sample Collection

  • Avoid foods with high sugar or acidity immediately before sample collection.
  • Document consumption of prescription/over-the-counter medications within the prior 12 hours.
  • Rinse mouth with water to remove food residue and then wait at least 10 minutes before collecting saliva.

During Sample Collection

  • Recommended Collection Volume: 200 µl*
  • Use a collection device that has been validated for the measurement of this analyte.
  • Follow your selected sample collection device/method protocol.

*Add 300 µl to the total volume of all tests for liquid handling loss

After Sample Collection

  • Record the time and date of specimen collection.
  • Refrigerate samples immediately (if possible) and freeze at or below -20°C (household freezer) when possible.
  • If samples are not shipped within 24 hours of collection, freeze samples at or below -20°C (household freezer) until shipping
  • Do not add preservatives to saliva samples unless they have been previously validated with the assay.
  • Consider aliquoting samples to avoid multiple freeze-thaws.
  • If shipping temperature can be maintained below 22°C, ambient overnight shipping is acceptable. If temperatures may be encountered during shipping above 22°C, ship on cold packs, overnight.
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