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Salivary Bioscience News

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Salivary Cortisol: Could it be our collective research focus has been too narrow?

Drop Date: October 2023 In This Drop: Salivary Cortisol: Could it be our collective research focus has been too narrow? By: Kristina Feghali and Douglas A. Granger If you are interested in the relationship between stress, biology, and behavior, you are probably aware of how salivary cortisol has been integrated into applied research to represent the activity [...]

Analysis of Salivary Microbiome in Caregiver-Child Dyads to explore the effects of Environmental Tobacco Smoke Exposure on Oral and Systemic Health

Human oral microbial communities are diverse, with implications for oral and systemic health. Oral microbial communities change over time; thus, it is important to understand how healthy versus …

Protected: Analytical Tactics for Salivary Analysis

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Gray Matter Volume Reduction and Raised Salivary Testosterone to Cortisol Ratio Related to Blast-Induced Neurotrauma

Blast-induced neurotrauma (BINT) frequently occurs during military training and deployment and has been linked to long-term neuropsychological and neurocognitive changes, and changes in brain…

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Dispatches from the Front Edge of Salivary Bioscience: A Commentary on “More Research is Needed”

Drop Date: September 2023 In This Drop: Dispatches from the Front Edge of Salivary Bioscience: A Commentary on “More Research is Needed” By: Kristina Feghali and Douglas A. Granger Commentary from Douglas Granger How many times has your attention been drawn to a headline about a new scientific discovery or a solution to a salient societal [...]

New Funding Opportunities on Salivary Components for Oral Health Released by the National Institute of Dental and Craniofacial Research

These funding opportunities encourage interdisciplinary research that harnesses the functional components of saliva towards…

Salivary alpha-amylase and cortisol association with Traumatic Brain Injury adjustment

Traumatic injury is linked increasingly to alterations in both stress response systems and psychological health. We investigated reactivity of salivary analytes of…

Environmental tobacco smoke exposure is associated with increased levels of metals in children’s saliva

Exposure to environmental tobacco smoke (ETS) has been associated with detectable levels of cotinine (a nicotine metabolite) in children’s saliva. However, tobacco…

Salivary Cortisol Awakening Response in Explosive Ordnance Disposal Technicians

Amassing evidence suggests that post-awakening salivary cortisol rhythms (changes in cortisol throughout the day) may indicate health status. We previously established summary parameters for…

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Insights on “Optimizing” Sample Size in Salivary Bioscience Research-Supplemental Figures

Drop Date: June 2023 Each graph portrays the distribution of salivary Coritsol Awakening Response, Cortisol Diurnal, and Trier Social Stress Test, searched from PubMed, based on the number of participants involved in each study. You’ll notice the distributions are non-normal and for this reason, we draw the reader’s attention to the median as the measure [...]
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Insights on “Optimizing” Sample Size in Salivary Bioscience Research

Drop Date: June 2023 By Douglas A. Granger and Kristina Feghali Insights on “Optimizing” Sample Size in Salivary Bioscience Research In the biobehavioral sciences, one of the most challenging issues is estimating statistical power. The underlying question is: "Does the study design include enough participants to rule out the possibility that observations made would be [...]

Salivary Cortisol and Salivary Alpha-Amylase measured to assess racial discrimination and the stress response

Perceived racial discrimination has been associated with the autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis activities-two major…

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Live the search for better science: A solution for sustained integration of Salivary Bioscience into your research

Drop Date: July 2023 Live the Search for Better Science: A Solution for Sustained Integration of Salivary Bioscience into Your Research Kristina Feghali and Douglas Granger There is a natural ebb and flow to activity in research groups that apply biobehavioral assessments. Work phases through proposing, awaiting funding decisions, project management, data collection, laboratory analyses, [...]
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Maximizing the Scientific Value of Saliva as a Biospecimen: A Guide for Research from Dr. Douglas Granger to the Research Community

Drop Date: April 2023 Maximizing the Scientific Value of Saliva as a Biospecimen: A Guide for Research from Dr. Douglas Granger to the Research Community Saliva attributes as a biospecimen include versatility, cost-effectiveness, ease of use, and low participant burden. Not surprisingly, oral fluid has rapidly become a research specimen of interest. This is especially [...]

The Emerging Field of Salivary Bioscience

Salivary bioscience is noteworthy in its history, as well as in the breadth and scope of its impact. The minimally invasive nature of sampling oral fluid allows for evaluation of individual and intra-individual change in…

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