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Salivary Bioscience News

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Salimetrics Expands Laboratory CLIA Certification for Saliva Testing

(February 2, 2022) Saliva testing is gaining in its utility to provide screening and diagnostic solutions, and Salimetrics is here to meet the needs of this growing field. With the recent expansion of Salimetrics' CLIA certification, the Saliva Laboratory reaches a new milestone in salivary bioscience. Salimetrics Saliva Laboratory’s experienced team, combined with the expanded [...]
COVID-19 in Saliva

Salimetrics’ Team Supports NIH Funded SARS-CoV-2 Post-Vaccination Study of Women’s Health

A new study seeks to investigate SARS CoV-2 vaccine effects on menstruation in female adolescents using salivary bioscience with the support of Salimetrics. While the current SARS-CoV-2 vaccines are considered safe and effective at preventing infection and hospitalizations, some women have reported menstrual cycle changes post-vaccination. Although incidents are low, changes in cycle length and […]

Salivary Bioscience News

Salivary Cortisol and alpha-amylase assayed in ethnic minorities depicts atypical diurnal rhythm

Stress response asymmetries in African American emerging adults exposed to chronic social adversity Wood, et al., (2021) The International Journal on the Biology of Stress ABSTRACT: Chronic stress is linked to social adversity and underlies many health disparities among ethnic minorities. Cortisol and salivary alpha-amylase (sAA) reflect sensitivity to adversity and are related to health […]

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Piloting Salivary Oxytocin – Observations and Opportunities for Research

Drop Date: November 2021 In This Drop: Piloting Salivary Oxytocin – Observations and Opportunities for Research The Salimetrics’ ground-breaking salivary oxytocin assay was designed specifically for saliva with Salimetrics’ unique knowledge and experience. Early results are in – not only does the assay range span the levels appropriate in saliva, but researchers can also differentiate [...]
Salivary Bioscience News

Trier Social Stress Test: Validating a Remote, TSST-Online Protocol

Validation of an online version of the Trier Social Stress Test in a study of adolescents Gunnar, et al., (2021) Psychoneuroendocrinology ABSTRACT: Introduction: The Trier Social Stress Test (TSST) is the most widely used protocol for activating a stress response of the hypothalamic-pituitary-adrenocortical (HPA) axis and other stress-mediating systems. A number of variants of the […]

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DHEA & DHEA(S) – The Stress Whisperers

Drop Date: October 2021 In This Drop: DHEA & DHEA(S) - The Stress Whisperers DHEA and cortisol are both hormones produced by the adrenal glands. While DHEA and cortisol are often measured independently as biomarkers, measuring the two hormones together can offer advanced insights for continued stress research. As salivary cortisol becomes more widespread, researchers [...]
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Infectious Diseases – Salivary Antibody Assays Track Exposure and Infection

Drop Date: August 2021 In This Drop: Infectious Diseases – Salivary Antibody Assays Track Exposure and Infection Although the state of the pandemic still seems to fluctuate from one day to the next, one thing remains clear: COVID-19 has shown us the benefits of saliva as a sample type are unprecedented for infectious disease research. [...]
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Statistical Approaches to Reduce Bias in Left-censored Salivary Data

Censored Data Considerations and Analytical Approaches for Salivary Bioscience Data Ahmadi, H. et al., (2021) Psychoneuroendorcinology ABSTRACT: Left censoring in salivary bioscience data occurs when salivary analyte determinations fall below the lower limit of an assay’s measurement range. Conventional statistical approaches for addressing censored values (i.e., recoding as missing, substituting or extrapolating values) may introduce […]

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Salivary Bioscience Research for Nordic Region Investigators

Have you met XboXLab? XboXLab is one of Salimetrics trusted international distributors covering the Nordic region (Norway, Finland, Sweden, Denmark). Their team consists of knowledgeable and experienced employees ready to assist researchers and suppliers. XboXLab and Salimetrics both align in their fundamental goal of fulfilling salivary bioscience research needs by providing customers with high-quality SalivaBio […]

Salivary Bioscience News

Blunted Morning Salivary Cortisol Associated with Cardiovascular Risk

Blunted circadian cortisol in children is associated with poor cardiovascular health and may reflect circadian misalignment Dai, W. et al., ( 2021) Psychoneuroendocrinology ABSTRACT: Objectives: Circadian cues in children (sunlight, exercise, diet patterns) may be associated with health outcomes. The primary objective was to assess associations of daily cortisol fluctuations (morning, night) with cardiovascular health […]

NR3C1 SNP Genotyping

Salivary cortisol correlates with DNA methylation in preterm infants

DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function Padbury, J. et al., (2021) Pediatric Research ABSTRACT: Background: There is increased risk of cardiovascular, metabolic, and hypertensive disorders in later life in the preterm population. We studied school-age children who had been born extremely premature who had undergone endocrine, […]

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Salivary SARS-CoV-2 IgG Assay: A practical alternative for screening and monitoring vaccine antibody response and seroprevalence.

Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers Heaney et al., ( 2021) medRxiv ABSTRACT: Oral fluid (hereafter saliva) offers a non-invasive sampling method for the detection of SARS-CoV-2 antibodies. However, data comparing performance of salivary tests against commercially-available serologic and neutralizing antibody (nAb) assays are […]

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Salimetrics Analytical Lab: Five ‘Value Adds’ for Principal Investigators

Drop Date: June 2021 In This Drop: Five ‘Value Adds’ for Principal Investigators For over 20 years, the Salimetrics saliva testing laboratory has remained a pillar of standardized methods for the salivary bioscience community, representing much more than just high-quality results. The scientific impact has been phenomenal and the collaborative environment, equal access, pay only [...]
Salivary Bioscience News

The role of Salivary Cortisol and Progesterone in female friendships

The endocrinology of female friendships: Cortisol and progesterone attunement after separation Rankin et al., (2021) Biological Psychology ABSTRACT: Friendships constitute important relationships, and often function to reduce stress, but have been under-studied. In mother-child dyads, infants coordinate their stress response with their caregivers without experiencing the stressor themselves. The current study used a modified version […]

Salivary Bioscience News

Increased altruism in children during distress may benefit from “tend-and-befriend” behavior

Children’s Altruism Following Acute Stress: The Role of Autonomic Nervous System Activity and Social Support V Alen et al., (2021) Developmental Science ABSTRACT: Altruistic behavior after stress exposure may have important health and psychological benefits, in addition to broader societal consequences. However, so far experimental research on altruism following acute stress has been limited to […]

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