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Piloting Salivary Oxytocin – Observations and Opportunities for Research
Drop Date: November 2021 In This Drop: Piloting Salivary Oxytocin – Observations and Opportunities for Research The Salimetrics’ ground-breaking salivary oxytocin assay was designed specifically for saliva with Salimetrics’ unique knowledge and experience. Early results are in – not only does the assay range span the levels appropriate in saliva, but researchers can also differentiate [...]
Trier Social Stress Test: Validating a Remote, TSST-Online Protocol
Validation of an online version of the Trier Social Stress Test in a study of adolescents Gunnar, et al., (2021) Psychoneuroendocrinology ABSTRACT: Introduction: The Trier Social Stress Test (TSST) is the most widely used protocol for activating a stress response of the hypothalamic-pituitary-adrenocortical (HPA) axis and other stress-mediating systems. A number of variants of the […]
DHEA & DHEA(S) – The Stress Whisperers
Drop Date: October 2021 In This Drop: DHEA & DHEA(S) - The Stress Whisperers DHEA and cortisol are both hormones produced by the adrenal glands. While DHEA and cortisol are often measured independently as biomarkers, measuring the two hormones together can offer advanced insights for continued stress research. As salivary cortisol becomes more widespread, researchers [...]
Infectious Diseases – Salivary Antibody Assays Track Exposure and Infection
Drop Date: August 2021 In This Drop: Infectious Diseases – Salivary Antibody Assays Track Exposure and Infection Although the state of the pandemic still seems to fluctuate from one day to the next, one thing remains clear: COVID-19 has shown us the benefits of saliva as a sample type are unprecedented for infectious disease research. [...]
Statistical Approaches to Reduce Bias in Left-censored Salivary Data
Censored Data Considerations and Analytical Approaches for Salivary Bioscience Data Ahmadi, H. et al., (2021) Psychoneuroendorcinology ABSTRACT: Left censoring in salivary bioscience data occurs when salivary analyte determinations fall below the lower limit of an assay’s measurement range. Conventional statistical approaches for addressing censored values (i.e., recoding as missing, substituting or extrapolating values) may introduce […]
Salivary Bioscience Research for Nordic Region Investigators
Have you met XboXLab? XboXLab is one of Salimetrics trusted international distributors covering the Nordic region (Norway, Finland, Sweden, Denmark). Their team consists of knowledgeable and experienced employees ready to assist researchers and suppliers. XboXLab and Salimetrics both align in their fundamental goal of fulfilling salivary bioscience research needs by providing customers with high-quality SalivaBio […]
Blunted Morning Salivary Cortisol Associated with Cardiovascular Risk
Blunted circadian cortisol in children is associated with poor cardiovascular health and may reflect circadian misalignment Dai, W. et al., ( 2021) Psychoneuroendocrinology ABSTRACT: Objectives: Circadian cues in children (sunlight, exercise, diet patterns) may be associated with health outcomes. The primary objective was to assess associations of daily cortisol fluctuations (morning, night) with cardiovascular health […]
Salivary cortisol correlates with DNA methylation in preterm infants
DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function Padbury, J. et al., (2021) Pediatric Research ABSTRACT: Background: There is increased risk of cardiovascular, metabolic, and hypertensive disorders in later life in the preterm population. We studied school-age children who had been born extremely premature who had undergone endocrine, […]
Salivary SARS-CoV-2 IgG Assay: A practical alternative for screening and monitoring vaccine antibody response and seroprevalence.
Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers Heaney et al., ( 2021) medRxiv ABSTRACT: Oral fluid (hereafter saliva) offers a non-invasive sampling method for the detection of SARS-CoV-2 antibodies. However, data comparing performance of salivary tests against commercially-available serologic and neutralizing antibody (nAb) assays are […]
Salimetrics Analytical Lab: Five ‘Value Adds’ for Principal Investigators
Drop Date: June 2021 In This Drop: Five ‘Value Adds’ for Principal Investigators For over 20 years, the Salimetrics saliva testing laboratory has remained a pillar of standardized methods for the salivary bioscience community, representing much more than just high-quality results. The scientific impact has been phenomenal and the collaborative environment, equal access, pay only [...]
The role of Salivary Cortisol and Progesterone in female friendships
The endocrinology of female friendships: Cortisol and progesterone attunement after separation Rankin et al., (2021) Biological Psychology ABSTRACT: Friendships constitute important relationships, and often function to reduce stress, but have been under-studied. In mother-child dyads, infants coordinate their stress response with their caregivers without experiencing the stressor themselves. The current study used a modified version […]
Increased altruism in children during distress may benefit from “tend-and-befriend” behavior
Children’s Altruism Following Acute Stress: The Role of Autonomic Nervous System Activity and Social Support V Alen et al., (2021) Developmental Science ABSTRACT: Altruistic behavior after stress exposure may have important health and psychological benefits, in addition to broader societal consequences. However, so far experimental research on altruism following acute stress has been limited to […]
Neuroscience Meets Salivary Bioscience: Interaction between sex, stress reactivity, and cingulum GFA
Sex-related differences in stress reactivity and cingulum white matter Wheelock, et al., ( 2021) Neuroscience ABSTRACT: The prefrontal cortex and limbic system are important components of the neural circuit that underlies stress and anxiety. These brain regions are connected by white matter tracts that support neural communication including the cingulum, uncinate fasciculus, and the fornix/stria-terminalis. […]
Zoom Webinar: Christopher D. Heaney, PhD., Johns Hopkins University – Using a Multiplex Salivary Antibody Assay to Measure SARS-CoV-2 Infection and Vaccination at Population-Scale
June 3rd, 2021 10:00am PST Zoom Webinar CHRISTOPHER D. HEANEY, PHD Bloomberg School of Public Health Johns Hopkins University ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of an ongoing pandemic that has infected millions of people across the globe. Informed implementation of government public health policies depends on accurate data on [...]