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SBB – The Curious Case of Salivary Alpha-Amylase
Drop Date: May 2015 In This Drop: Impact and Scientific Critical Mass of Salivary Alpha-Amylase Salivary alpha-amylase (sAA) is a surrogate measure of the autonomic/sympathetic nervous system (ANS) component of the stress response (see Granger et al., 2007; Nater et al., 2009). What may be surprising to you is the rapid pace that salivary alpha-amylase [...]
SBB- Stress, Sex Hormones & Emotional Memory
Drop Date: March 2012 In This Drop: Sex Hormones in Saliva and Differences in Learning and Memory It is a common experience for humans to have vivid and long-lasting memories of events or periods in their lives that were stressful or emotionally arousing. In order to understand the influence that stress has on memory, scientists [...]
SBB – Novel Salivary Biomarkers of ANS Activity
Drop Date: January 2012 In This Drop: Salivary Biomarkers of ANS Activity Many studies in the behavioral and developmental sciences now utilize a multiple-biomarker approach. For example, salivary cortisol and salivary alpha-amylase (sAA) are often measured together as markers of activity in the hypothalamic-pituitary-adrenal axis (HPAA) and autonomic nervous system (ANS), respectively. Since these two [...]
SBB – Inflammation, Psychosocial Stress, and Salivary Cytokines
Drop Date: November 2011 In This Drop: Salivary Bioscience, Inflammation and its Effects on Human Health The study of inflammation and its effects on human health has been a major topic of interest in recent decades. Numerous studies have observed that a low-level state of systemic inflammation is a common feature found in metabolic diseases [...]
SBB – Smoking, Salivary Cotinine and Child Health
Drop Date: July 2011 In This Drop: Salivary Cotinine, Second-hand Smoke, and Child Health In spite of clear evidence that the use of tobacco products leads to nicotine addiction and numerous adverse health effects, smoking and oral tobacco use continue to be common in many countries around the world. Researchers interested in child development are [...]
SBB – Salivary Biomarkers of Inflammation
Drop Date: April 2011 In This Drop: Salivary Bioscience and Inflammation Bio-medical researchers routinely measure biomarkers such as cytokines (IL-6, IL-1ß, TNF-α) and C-reactive protein (CRP) in blood in order to assess the presence of inflammation. In order to avoid the cost, inconvenience, discomfort, and bio-hazard risk associated with blood drawing, however, researchers have more [...]
SBB – Stress, the HPA Axis and Aging
Drop Date: February 2011 In This Drop: Stress, the HPA Axis and Aging As populations around the world grow increasingly older, the study of factors that can lead to unhealthy aging has become an important focus in bio-behavioral research. In particular, the ever-present psychological and physical stress found in modern societies is thought to be [...]
Saliva Collection Handbook
About Salimetrics Salimetrics leads the industry in supporting thousands of salivary bioscience researchers around the world with the most accurate, highest-quality, salivary assays, saliva collection devices, and saliva testing services. Dedicated to the field of salivary bioscience, Salimetrics assays have been used in more saliva-related published papers than any other salivary assay in the field. [...]
SBB – Improving Saliva Study Results
Drop Date: November 2010 In This Drop: Ensuring Accurate and Reproducible Salivary Bioscience Ensuring that assay results are accurate and meaningful is a key part of every study. To achieve this goal when saliva is used as a testing fluid, researchers need to be aware that biomarkers enter saliva through a number of different pathways. [...]
SBB – The Cortisol Awakening Response and Circadian Cortisol Regulation
Drop Date: June 2010 In This Drop: What Will You Discover Today? The cortisol awakening response (CAR) is a surge in cortisol production that occurs in most healthy people shortly after waking in the morning. The CAR has attracted a great deal of attention since its recognition in 1997, and in 2009-2010 alone nearly 300 [...]
SBB – Reproductive and Sexual Health
Drop Date: April 2010 In This Drop: Salivary Bioscience for Reproductive and Sexual Health Research This issue of The Spit Report focuses on the steroid sex hormones and their relationship to reproductive and sexual health. Because the measurement of steroid hormones in saliva is simple and less stressful compared to blood, salivary testing for cortisol [...]
SBB – Exercise, Sports Science, and Medicine
Drop Date: January 2010 In This Drop: Salivary Bioscience and Sports Medicine Whether going to a stadium to watch highly skilled athletes compete or simply engaging in some casual weekend fun of their own, humans seem to be drawn to competitive physical activity. Professional sports franchises around the globe are truly big businesses, and owners, [...]
Measuring SIgA in Saliva
SIgA Levels in Saliva are Affected by Its Mechanism of Entry Unlike the various other salivary anti-microbial proteins that are synthesized directly in the saliva glands, or serum-derived analytes such as the steroid hormones that enter saliva by passive diffusion, Secretory IgA (SIgA) is a product of the adaptive immune system. Plasma B cells formed [...]
SBB – Special Issue: Periodontal Disease
Drop Date: November 2009 In This Drop: Salivary Biomarkers of Periodontal Disease Periodontal disease is a common inflammatory condition of the oral cavity caused by the body's efforts to combat chronic bacterial infection in the tissues that support the teeth. If left untreated, it can lead to irreversible tissue damage and ultimately to tooth loss, [...]