Contact: Salimetrics (USA)
Disorganized attachment in infants associated with elevated salivary CRP
Increased levels of inflammation among infants with disorganized histories of attachment Author: Measelle JR, et al. (2017), Behavioural Brain Research Early life adversity is associated with adult elevations of inflammatory markers such as circulating levels of C-reactive protein (CRP). Few studies have examined inflammation levels during infancy nor the associations between sources of adversity and […]
Non-invasive oral fluid immunoassay for hepatitis E virus (HEV) infection
Development of an oral fluid immunoassay to assess past and recent hepatitis E virus (HEV) infection Author: Pisanic N, et al. (2017), Journal of Immunological Methods BACKGROUND: Hepatitis E virus (HEV) infection causes significant morbidity and mortality worldwide, particularly among pregnant women. In clinical settings blood-based testing protocols are commonly used to diagnose HEV infection, […]
Childhood maltreatment affects cortisol and alpha-amylase stress reactivity
Patterns of cortisol and alpha-amylase reactivity to psychosocial stress in maltreated women Author: Mielock AS, et al. (2017), Journal of Affective Disorders BACKGROUND: Childhood maltreatment can trigger enduring changes in major stress response systems, particularly in the context of major depressive disorder (MDD). However, the relative impact of maltreatment versus MDD on hypothalamic-pituitary-adrenal axis and […]
Differences in HPA axis activity are a function of age and cumulative risk
Individual differences in the activity of the hypothalamic pituitary adrenal axis: Relations to age and cumulative risk in early childhood Author: Holochwost SJ, et al. (2017), Psychoneuroendocrinology This study examined individual differences in the function of the hypothalamic-pituitary-adrenal (HPA) axis with regard to age and cumulative risk during challenging laboratory tasks administered at 6, 12, […]
Association of salivary adiponectin with serum and inflammatory markers
Adiponectin: Serum-Saliva Associations and Relations with Oral and Systemic Markers of Inflammation Author: Riis JN, et al. (2017), Peptides This study addresses gaps in our understanding about the validity and utility of using salivary adiponectin to index serum adiponectin levels. Matched blood and saliva samples were collected on a single occasion from healthy adults (n=99; […]
SBB – Measuring Multiple Analytes
Drop Date: May 2017 In This Drop: Keeping the Science in Saliva When Measuring Multiple Analytes Leading salivary bioscience researchers continue to map the biological landscape by including cutting-edge, multisystem measurements in their research. A single saliva sample can provide robust data for multiple analytes, when handled correctly. How to Measure Multiple Salivary Analytes from [...]
SBB – Measuring Cortisol & the HPA Axis
Drop Date: October 2016 In This Drop: Current State of Salivary Cortisol Research and the HPA axis Recent research provides a clearer link between stress and its impact on health. Whether that stress is acute or chronic, it can affect the levels of cortisol produced by the human body, which is measurable with a range [...]
SBB – Salivary Bioscience as a building block for the RDoC matrix
Drop Date: August 2016 In This Drop: Salivary Bioscience and the RDoC Matrix For more than two decades, Salivary Bioscience has been unlocking effective interdisciplinary opportunities to engage investigators studying mental health. Salivary cortisol has been at the leading edge of this effort and now joins many other salivary analytes and genetic markers as key [...]
SBB – Better Together – Salivary Testosterone & Cortisol
Drop Date: June 2016 In This Drop: Measuring Salivary Testosterone and Cortisol Renewed interest by the research community has focused on the salivary testosterone/cortisol (T/C) ratio and its supporting biological mechanisms. In this issue of the Salivary Bioscience Bulletin, we explore the scientific literature and provide a summary of our findings. Research suggests that testosterone [...]
SBB – A Milestone in Salivary Cortisol Research
Drop Date: April 2015 In This Drop: A Milestone in Salivary Cortisol Research Last year marked a milestone in Salivary Bioscience history. Salivary Cortisol has now been featured in over 25,000 scientific research publications. For this issue of the Salivary Bioscience Bulletin, we wanted to take a moment to thank the scientific community for allowing [...]
SBB – Oxytocin Receptor Genotyping From Saliva
Drop Date: March 2016 In This Drop: Salivary DNA + OXTR = Great Research Studies of the Oxytocin Receptor Gene (OXTR) have provided critical information about the downstream effects of oxytocin on a variety of behaviors including stress, anxiety, social memory, sexual and aggressive behavior, bonding, and maternal behavior (1). The OXTR protein is part [...]
SBB – Best Practices for Saliva Swab Collection
Drop Date: February 2016 In This Drop: Best Practices for Saliva Swab Collection One of the first saliva swab collection devices designed to collect saliva for the measurement of salivary cortisol was the Sarstedt Salivette®. Over time and because of its simple design, the use of the term Salivette® in the literature became synonymous with [...]
SBB – Salivary DNA Genotyping
Drop Date: December 2015 In This Drop: 1+1=3 (Biomarkers + DNA = Great Research) The latest research continues to reinforce the correlation between SNP-related associations and genetic biology, behaviors, and diseases. But did you know that you can easily and affordably incorporate accurate, high-quality DNA analysis from saliva and get results that are identical to [...]
SBB – Mapping the Health Implications of Elevated Salivary Uric Acid
Drop Date: November 2015 In This Drop: Salivary Uric Acid With a strong serum-saliva correlation, regular monitoring of uric acid levels with saliva testing shows a strong potential when defining the status of this key biological marker, while also offering the option to efficiently study preventative health effects and combat what can eventually lead to [...]