Gray Matter Volume Reduction and Raised Salivary Testosterone to Cortisol Ratio Related to Blast-Induced Neurotrauma
Blast-induced neurotrauma (BINT) frequently occurs during military training and deployment and has been linked to long-term neuropsychological and neurocognitive changes, and changes in brain…
Dispatches from the Front Edge of Salivary Bioscience: A Commentary on “More Research is Needed”
Drop Date: September 2023 In This Drop: Dispatches from the Front Edge of Salivary Bioscience: A Commentary on “More Research is Needed” By: Kristina Feghali and Douglas A. Granger Commentary from Douglas Granger How many times has your attention been drawn to a headline about a new scientific discovery or a solution to a salient societal [...]New Funding Opportunities on Salivary Components for Oral Health Released by the National Institute of Dental and Craniofacial Research
These funding opportunities encourage interdisciplinary research that harnesses the functional components of saliva towards…
Salivary alpha-amylase and cortisol association with Traumatic Brain Injury adjustment
Traumatic injury is linked increasingly to alterations in both stress response systems and psychological health. We investigated reactivity of salivary analytes of…
Environmental tobacco smoke exposure is associated with increased levels of metals in children’s saliva
Exposure to environmental tobacco smoke (ETS) has been associated with detectable levels of cotinine (a nicotine metabolite) in children’s saliva. However, tobacco…
Salivary Cortisol Awakening Response in Explosive Ordnance Disposal Technicians
Amassing evidence suggests that post-awakening salivary cortisol rhythms (changes in cortisol throughout the day) may indicate health status. We previously established summary parameters for…
Insights on “Optimizing” Sample Size in Salivary Bioscience Research-Supplemental Figures
Drop Date: June 2023 Each graph portrays the distribution of salivary Coritsol Awakening Response, Cortisol Diurnal, and Trier Social Stress Test, searched from PubMed, based on the number of participants involved in each study. You’ll notice the distributions are non-normal and for this reason, we draw the reader’s attention to the median as the measure [...]Insights on “Optimizing” Sample Size in Salivary Bioscience Research
Drop Date: June 2023 By Douglas A. Granger and Kristina Feghali Insights on “Optimizing” Sample Size in Salivary Bioscience Research In the biobehavioral sciences, one of the most challenging issues is estimating statistical power. The underlying question is: "Does the study design include enough participants to rule out the possibility that observations made would be [...]Salivary Cortisol and Salivary Alpha-Amylase measured to assess racial discrimination and the stress response
Perceived racial discrimination has been associated with the autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis activities-two major…
Live the search for better science: A solution for sustained integration of Salivary Bioscience into your research
Drop Date: July 2023 Live the Search for Better Science: A Solution for Sustained Integration of Salivary Bioscience into Your Research Kristina Feghali and Douglas Granger There is a natural ebb and flow to activity in research groups that apply biobehavioral assessments. Work phases through proposing, awaiting funding decisions, project management, data collection, laboratory analyses, [...]Maximizing the Scientific Value of Saliva as a Biospecimen: A Guide for Research from Dr. Douglas Granger to the Research Community
Drop Date: April 2023 Maximizing the Scientific Value of Saliva as a Biospecimen: A Guide for Research from Dr. Douglas Granger to the Research Community Saliva attributes as a biospecimen include versatility, cost-effectiveness, ease of use, and low participant burden. Not surprisingly, oral fluid has rapidly become a research specimen of interest. This is especially [...]The Emerging Field of Salivary Bioscience
Salivary bioscience is noteworthy in its history, as well as in the breadth and scope of its impact. The minimally invasive nature of sampling oral fluid allows for evaluation of individual and intra-individual change in…
Exploring Salivary Cortisol Patterns in Zoo-Housed Apes: A tool for welfare assessment
Monitoring changes in cortisol levels is a widespread tool for measuring individuals’ stress responses. However, an acute increase in cortisol levels does not necessarily denote an individual in…
Salivary Cortisol and sAA reactivity to TSST differs in Cannabis users and non-users
To advance our understanding of the health-related consequences of chronic cannabis use, this study examined hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) reactivity and regulation in…
Salivary cortisol and oxytocin related to reduced youth anxiety through novel interventions, such as equine-assisted adaptive riding program
Reining in Anxiety (RiA) is a therapeutic program for youth with mild to moderate anxiety delivered in a therapeutic riding setting by Certified Therapeutic Riding Instructors. RiA was developed after a review of the evidence base for…