Contact: Salimetrics (USA)
NAVAL MEDICAL CENTER SAN DIEGO · RESEARCH & INNOVATION DAY
Salimetrics delivers non-invasive salivary biomarker research and laboratory services to the military health community.
Enabling field-deployable, repeatable measurement of stress, hormones, immune function, and more.
25+
Years in Salivary Bioscience
10k+
Published Research Citations
CLIA
Certified CoreLab+
50+
Military-Relevant Biomarkers
ABOUT SALIMETRICS
The Global Leader in Salivary Bioscience
Founded in 1998, Salimetrics has pioneered the standardization of saliva collection, processing, and analysis for research and diagnostics. Our assays have been cited in more published saliva research than any other provider in the world.
For the military health community, saliva offers a critical advantage: non-invasive, field-deployable collection that requires no needles, no phlebotomist, and minimal cold chain. Participants self-collect — enabling large-scale repeated sampling in operational settings.
CORE CAPABILITIES
| ▸ Salivary Cortisol & Stress Hormone Profiling |
| ▸ DHEA, Testosterone & Anabolic Hormone Panels |
| ▸ Alpha-Amylase (sAA): Autonomic Stress Marker |
| ▸ Inflammatory Markers (CRP, Cytokines, SIgA) |
| ▸ Chromogranin A (CgA): PTSD Resilience Marker |
| ▸ Dried Blood Spot (DBS) Biomarker Sampling |
| ▸ DBS HbA1c & DBS C-Reactive Protein |
| ▸ DNA / Genomic Testing via Saliva |
| ▸ Field-Deployable Collection Protocols |
| ▸ CLIA-Certified CoreLab+ Analysis |
| ▸ Study Design & Grant Consultation |
RESEARCH PORTFOLIO
Military Studies
Salimetrics assays and services have supported a wide range of military health research — from elite special operations forces to combat casualty care training.
CORTISOL · ALPHA-AMYLASE · STRESS
Stress Reactivity & Performance in Army Nurses
Simulated combat stress triggered strong physiological responses, with greater stress reactivity and slower recovery linked to poorer performance.
Army Nurses · N=38 · Simulation · Performance
MULTIANALYTE PANELS · HUMAN PERFORMANCE
Salivary Bioscience in Extreme Operational Environments
Salivary bioscience enables non-invasive monitoring of physical and behavioral health in extreme, environments, supporting longitudinal assessment of operational decision-making.
Military & Extreme Environments · Review
DHEA · DHEA-S · TESTOSTERONE · NGF · sAA
DHEA(S) and Resilience in Military Personnel
DHEA and DHEA-S were linked to anabolic, neuroprotective, and sympathetic activity, with distinct roles across hormone production, neurotrophic signaling, and stress response.
Active Duty Military Men · N=42 · Cross-Sectional
CORTISOL (CAR)
Service Dogs & Cortisol Awakening Response in PTSD
Veterans with PTSD who had a service dog showed a higher cortisol awakening response and improved psychological wellbeing.
Post-9/11 Veterans · N=73 · PTSD
DHEA · TESTOSTERONE
Anabolic Hormone Profiles in Elite Military Men
DHEA and testosterone show stable, diurnal anabolic patterns in elite military men, supporting resilience, performance, and stress adaptation.
Active Duty Navy SEALs · N=58 · Repeated Measures (2 Days)
MULTIPLE SALIVARY BIOMARKERS
Saliva as a Window into Human Biology
Saliva provides a noninvasive way to measure hormones, immune markers, and stress physiology across real-world settings.
Immune markers · DNA · Environmental exposures
KEY SALIVA ANALYTES
Salivary Biomarkers for Military Health
From acute sympathetic activation to chronic hormonal dysregulation, Salimetrics covers the full physiological stress spectrum, all from a non-invasive saliva sample.
Cortisol
Gold-standard HPA-axis stress marker. Circadian profiling and awakening response in operational contexts.
Alpha-Amylase
Sympathetic nervous system proxy. Rapid acute stress response. Detectable within minutes.
Testosterone & DHEA
Anabolic hormone profiling for readiness, resilience, and recovery monitoring.
Secretory IgA
Mucosal immune function. Suppressed under chronic stress. Sensitive marker of overtraining.
C-Reactive Protein
Non-invasive salivary CRP — validated as an inflammatory biomarker in multiple populations.
Chromogranin A
Neuroendocrine stress marker with utility in PTSD resilience and sympathoadrenal profiling.
Oxytocin
Social bonding and unit cohesion research. Validated extraction-free assay protocols.
Melatonin
Circadian disruption and sleep quality assessment across deployment and readjustment phases.
ALSO AVAILABLE
Dried Blood Spot (DBS) Testing
Salimetrics also supports Dried Blood Spot collection and analysis — offering a complementary non-invasive method for biomarkers that are best measured in blood. DBS cards are collected via a simple fingerstick and can be mailed to our CLIA-certified CoreLab+ for analysis.
DBS HbA1c
Glycated hemoglobin for assessing blood sugar regulation and metabolic health in long-term stress and deployment contexts.
DBS C-Reactive Protein
Systemic inflammatory marker from a simple dried blood spot. Ideal for field or remote collection where venipuncture isn’t feasible.
DBS Cytokine Panel (3-plex)
Simultaneous measurement of IL-6, IL-10, and TNF-alpha from a single dried blood spot. Ideal for immune profiling in military populations.
WHY DBS?
| ✓ Fingerstick collection. No venipuncture required |
| ✓ Stable at room temperature. Ships without cold chain |
| ✓ Mailed directly from the field or participant’s home |
| ✓ Combines with saliva samples for multi-biospecimen panels |
| ✓ CLIA-certified analysis through Salimetrics CoreLab+ |
WHY PARTNER WITH US
Built for Rigorous
Military Research
01 Non-Invasive Field Collection
| No needles, no phlebotomist, no cold chain at point of collection. Participants self-collect, enabling repeated sampling in operational environments. |
02 CLIA-Certified CoreLab+
| Clinical-grade accuracy backed by decades of validated methodology. Millions of saliva and DBS samples processed with rigorous QC. |
03 Expert Study Design Support
| Work directly with our scientific team to design biomarker protocols, navigate grant proposals, and optimize your collection strategy. |
04 Participant-Friendly Protocols
| Validated Participant Sampling Packs ensure sample integrity from field to lab, reducing variability and improving reproducibility at scale. |
| 🏥 CLIA Certified Laboratory
Federal certification for clinical laboratory accuracy and diagnostic reliability.
|
| 📋 IRB-Compatible Protocols
Fully documented for IRB submissions and DoD research compliance.
|
| 🔬 Validated Assay Kits
Developed and validated specifically for salivary matrices.
|
| 📦 Standardized Collection Tools
Salimetrics devices with published stability data for field deployment.
|
| 🤝 DoD & Federal Research Partners
Longstanding collaborations with DoD-funded programs and federal agencies. |
CONNECT WITH SALIMETRICS
Ready to Add Saliva or DBS to
Your Research?
Our team is at the booth today. Reach us to discuss study design, available assays, saliva and DBS collection, and CoreLab+ services for your military health program.