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Robust relationship between DHEA and emerging symptoms of pathological worry during adolescence
Increased dehydroepiandrosterone (DHEA) is associated with anxiety in adolescent girls Mulligan EM, et al., (2020) Psychneuroendocrinology ABSTRACT: The pubertal period is a time of rapid increase in the incidence of anxiety disorders, and thus, pubertal hormones may play a role in the precipitation of anxious psychopathology. DHEA, a steroid hormone that surges in adolescence, has […]
Impacting Associations Between Salivary Cortisol and Alpha-Amylase and Child Depressive Symptoms.
Child depressive symptoms: Associations with salivary cortisol and alpha amylase in two distinct challenges Khoury JE, et al., ( 2020) Biological psychology ABSTRACT: Child depression has been inconsistency linked to cortisol and salivary alpha-amylase (sAA) reactivity. This study assessed three factors that contribute to inconsistencies: 1) the differential effectiveness of laboratory challenges to elicit cortisol […]
Salimetrics Online Workshops – Translating the Best Guide, “Foundations of Interdisciplinary Saliva Research & Applications”, into Easy Steps for Research Applications
(March 31, 2021) Based on the book “Salivary Bioscience - Foundations of Interdisciplinary Saliva Research and Applications”, Salimetrics has expanded its workshop series to provide practical steps for research and diagnostics using saliva as the specimen. For over 20 years, Salimetrics has supported the Salivary Bioscience field by providing best methods for sample collection and [...]
New Recommendations for Repeatability in Salivary Bioscience Data
The case for the repeatability intra-class correlation as a metric of precision for salivary bioscience data: Justification, assessment, application, and implications Riis, JL. et al., (2021) Psychoneuroendocrinology Summary Highlight: This study highlights how advances in salivary assay precision, combined with a qualified laboratory reduces the necessity to test samples in duplicate. As best practice standards [...]
Salimetrics Launches Saliva Testing with Industry-Leading SARS-CoV-2 IgG Antibody Multiplex Assay Used in Vaccine Clinical Trials
(March 16, 2021) Salimetrics now offers multiplex testing for antibodies against SARS-CoV-2 Nucleocapsid, Spike 1, and Spike 1 Receptor Binding Domain (RBD) using a single, easy-to-collect saliva sample. Researchers now have unparalleled access to saliva collection devices and COVID-19 antibody saliva testing on a robust and validated platform. The Salimetrics SalivaLab R&D Testing facility has [...]
Univ. of Calgary Employment Opportunity: Postdoctoral Scholar in Child and Youth Mental Health and Neurodevelopment
Area: Cumming School of Medicine, Departments of Pediatrics and Community Health Sciences Duration: One year; renewable for up to two additional years Salary: $55,000-60,000/year plus Plan C health benefits through Alberta Blue Cross. The Cumming School of Medicine (Departments of Community Health Sciences and Pediatrics) at the University of Calgary is seeking a postdoctoral scholar […]
Antibody levels in saliva as a surrogate measure of systemic immunity to SARS-CoV-2
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients Baweleta I, et al., (2020) Science Immunology ABSTRACT:While the antibody response to SARS-CoV-2 has been extensively studied in blood, relatively little is known about the antibody response in saliva and its relationship to systemic antibody levels. Here, we profiled by enzyme-linked […]
Saliva-Based Hormone Monitoring for IVF: New Data Presents High Patient Serum-Saliva Correlations for Estradiol
(March 3, 2021) A large, multi-site, international In Vitro Fertilization (IVF) Study supported by Salimetrics recently published results indicating potential advances in fertility treatment utilizing saliva samples. In a multi-site study published in RBMO, “A multi-centre international study of salivary hormone oestradiol and progesterone measurements in ART monitoring,” In Vitro Fertilization (IVF) specialists examined whether [...]
Guidelines for measuring salivary cytokines
Best Practice Recommendations for the Measurement and Interpretation of Salivary Proinflammatory Cytokines in Biobehavioral Research Riis J, et al., ( 2020) Brain, Behavior, and Immunity ABSTRACT:Despite the integration of salivary inflammatory cytokines into research across the biobehavioral, psychological, clinical, and health-related disciplines, there is little guidance regarding the biospecimen collection, handling, and storage practices that […]
Unhealthy behaviors and stress-related morbidities may be associated with perceived racial discrimination
Feasibility and acceptability of intensive, real‐time biobehavioral data collection using ecological momentary assessment, salivary biomarkers, and accelerometers among middle‐aged African Americans. Nam S et al., ( 2020). Research Nursing Health ABSTRACT:Perceived racial discrimination is linked to unhealthy behaviors and stress-related morbidities. A compelling body of research indicates that perceived racial discrimination may contribute to health […]
Salivary Interleukin-6 as a potential non-invasive biomarker for Huntington’s Disease progression
Levels of Interleukin-6 in Saliva, but Not Plasma, Correlate with Clinical Metrics in Huntington’s Disease Patients and Healthy Control Subjects. Corey-Bloom et al. (2020) International Journal of Molecular Sciences ABSTRACT:Growing evidence suggests that inflammatory responses, in both the brain and peripheral tissues, contribute to disease pathology in Huntington’s disease (HD), an inherited, progressive neurodegenerative disorder […]
Increases in adolescent’s salivary cortisol levels may show adolescent-driven stress transmission in families
Daily parent-adolescent cortisol associations: Unpacking the direction of effects. Lippold MA, et al., (2020) Psychoneuroendocrinology ABSTRACT:Prior studies suggest bidirectional relationships between parent and adolescent behavior. This study examined how parents and their adolescent child’s cortisol patterns are associated across days and if there are bidirectional associations between parent and child cortisol. Participants included two samples […]
Improved salivary HCMV IgG antibody assays may be a viable option for serum testing
Correspondence between Cytomegalovirus IgG Levels Measured in Saliva and Serum Riis, JL. Et al. (2020) Journal of Clinical Medicine. ABSTRACT:Cytomegalovirus (HCMV) infects more than 80% of the global population. While mostly asymptomatic, HCMV infection can be serious among the immunocompromised, and it is implicated in chronic disease pathology in adulthood. Large-scale minimally-invasive HCMV screening could […]
Methods for highly sensitive measurement of SARS-CoV-2 viral RNA and antibodies from a single saliva sample
Ultrasensitive measurement of both SARS-CoV2 RNA and serology from saliva D Ter-Ovanesyan et al., (2021) medRxiv ABSTRACT: Tests for COVID-19 generally measure SARS-CoV2 viral RNA from nasal swabs or antibodies against the virus from blood. It has been shown, however, that both viral particles and antibodies against those particles are present in saliva, which is […]
Behavior problems in youth may show a higher salivary cortisol – alpha-amylase coordination
The within-person coordination of HPA and ANS activity in stress response: Relation with behavior problems FR Chen et al., (2020) Psychoneuroendocrinology ABSTRACT: This study tests the within-person coordination of HPA and ANS activity in response to stress and examines for the first time the association between such coordination and behavior problems in minority urban children. […]