Nonhuman primates mirror human early life adversity & salivary cortisol/alpha-amylase responses
Effects of early life adversity on cortisol/salivary alpha-amylase symmetry in free-ranging juvenile rhesus macaques. Author: Petrullo LA, et al (2016), Horm Behav. Early life adversity (ELA) affects physiological and behavioral development. One key component is the relationship between the developing Hypothalamic-Pituitary-Adrenal (HPA) axis and the Sympathetic Nervous System (SNS). Recent studies suggest a relationship between […]
Sympathetic and hypothalamic-pituitary-adrenal asymmetry in generalized anxiety disorder
Developmental origins of infant stress reactivity profiles: A multi-system approach. Author: Reeves JW, et al (2016), Psychophysiology Physiologic investigations of generalized anxiety disorder (GAD) have skewed toward assessment of the autonomic nervous system, largely neglecting hypothalamic-pituitary-adrenal (HPA) axis variables. Although these systems coordinate, suggesting a degree of symmetry, to promote adaptive functioning, most studies opt […]