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Maximizing the Scientific Value of Saliva as a Biospecimen: A Guide for Research from Dr. Douglas Granger to the Research Community
Drop Date: April 2023 Maximizing the Scientific Value of Saliva as a Biospecimen: A Guide for Research from Dr. Douglas Granger to the Research Community Saliva attributes as a biospecimen…
Methods for highly sensitive measurement of SARS-CoV-2 viral RNA and antibodies from a single saliva sample
…results suggest the utility of combining viral RNA and serology testing from saliva, a single easily accessible biofluid. View Abstract Keywords: COVID-19, serology, antibody testing, SARS-CoV-2 RNA test, nasal swabs…
Salivary 17 Alpha-OHP
17α-hydroxyprogesterone (17-OH progesterone or 17OHP) is a steroid hormone produced in the adrenal gland and gonads. (1,2,3) It is synthesized from progesterone, and it serves primarily as a precursor compound…
Salivary Interleukin-13
Human interleukin-13 (IL-13) is secreted by a variety of immune cells as a 15.8 kDa, glycosylated monomeric cytokine involved in a number of biological processes. It stimulates B-cell proliferation, macrophage…
Salivary Interleukin-7
Human Interleukin 7 (IL-7) activity is important for every stage of T cell development and survival of naïve T cells and generation and maintenance of CD4 and CD8 T cell…
Salivary Interleukin-5
…saliva and levels are elevated in asthmatic patients (5). Salivary biomarkers for asthma are appealing to researchers as they enable on demand sample collection, for example before and after asthmatic…
Salivary Osteocalcin
Osteocalcin (also known as OCN, OC, and Bone-Gla-Protein (BGP) or bone gamma-carboxyglutamic acid-containing protein (BGLAP)), is a bone-derived hormone protein released solely by osteoblasts during bone remodeling in vertebrates. Research…
Salivary Interleukin-17A
…lungs of patients with asthma and COPD. It comes as no surprise that IL-17A is a popular drug target and drugs (ixekizumab, secukinumab ) have been approved by the FDA…
Salivary Aldosterone
Recent studies have shown that primary aldosteronism (PA) is the most common cause of secondary hypertension with a prevalence of approximately 5-10% among all hypertensive patients and an even higher…
Salivary Interleukin-12p70
Human interleukin-12p70 (IL-12p70) activates T cells and natural killer cells that stimulate the production of IFN-γ. It is involved in a number of disorders including periodontitis (1) and chronic toxoplasmosis…
Salivary Interleukin-10
Human interleukin-10 (IL-10). IL-10 is mainly produced by monocytes and some lymphocytes as a 20.5 kDa, glycosylated homodimeric protein. It is an anti-inflammatory cytokine that inhibits the synthesis of numerous…
Salivary Interleukin-2
IL-2 Human interleukin-2 (IL-2) has several roles in the immune system, immune tolerance and immunity against pathogens, primarily by its direct effects on T lymphocytes. In general, depending on the…
The Entry of Substances into Saliva and the Effect of Flow Rate on Their Concentrations
…blood components pass easily through the capillary walls, bathing the saliva glands. The neutral steroids diffuse readily through the lipo-protein membranes of the secretory cells in the saliva glands and…
Measuring salivary transferrin to determine blood contamination levels
…developed a statistical method to test the amount of blood contamination that needs to be avoided in saliva samples for the following hormones: cortisol, estradiol, progesterone, testosterone and oxytocin. DESIGN…
Salivary DLMO Profile
Need a DLMO Test? Salimetrics all-inclusive, Home DLMO Test Kit for researchers, clinicians, or personal use is now available. Dim Light Melatonin onset as a biomarker for the analysis of…